KEGG   DRUG: Linagliptin and metformin hydrochloride
Entry
D10264            Mixture   Drug                                   

Name
Linagliptin and metformin hydrochloride;
Jentaduet (TN)
Product
Component
Linagliptin [DR:D09566], Metformin hydrochloride [DR:D00944]
Remark
ATC code: A10BD11
Product: D10264<US>
Efficacy
Antidiabetic
  Disease
Type 2 diabetes mellitus [DS:H00409]
Comment
Linagliptin is a P-glycoprotein (P-gp) substrate.
Metabolism
Transporter: ABCB1 [HSA:5243]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BD Combinations of oral blood glucose lowering drugs
     A10BD11 Metformin and linagliptin
      D10264  Linagliptin and metformin hydrochloride <US>
USP drug classification [BR:br08302]
 Blood Glucose Regulators
  Antidiabetic Combinations
   Linagliptin/ Metformin Hydrochloride
    D10264  Linagliptin and metformin hydrochloride
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D10264
Drug metabolizing enzymes and transporters [br08309.html]
 Drug transporters
  D10264
Other DBs
PubChem: 163312295
LinkDB

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