KEGG   DRUG: ClazakizumabHelp
Entry
D10312                      Drug                                   

Name
Clazakizumab (USAN/INN)
Formula
C6426H9972N1724O2032S42
Exact mass
145147.8243
Mol weight
145236.9975
Sequence
(Heavy chain)
EVQLVESGGG LVQPGGSLRL SCAASGFSLS NYYVTWVRQA PGKGLEWVGI IYGSDETAYA
TSAIGRFTIS RDNSKNTLYL QMNSLRAEDT AVYYCARDDS SDWDAKFNLW GQGTLVTVSS
ASTKGPSVFP LAPSSKSTSG GTAALGCLVK DYFPEPVTVS WNSGALTSGV HTFPAVLQSS
GLYSLSSVVT VPSSSLGTQT YICNVNHKPS NTKVDKRVEP KSCDKTHTCP PCPAPELLGG
PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYA
STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSREE
MTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW
QQGNVFSCSV MHEALHNHYT QKSLSLSPGK
(Light chain)
AIQMTQSPSS LSASVGDRVT ITCQASQSIN NELSWYQQKP GKAPKLLIYR ASTLASGVPS
RFSGSGSGTD FTLTISSLQP DDFATYYCQQ GYSLRNIDNA FGGGTKVEIK RTVAAPSVFI
FPPSDEQLKS GTASVVCLLN NFYPREAKVQ WKVDNALQSG NSQESVTEQD SKDSTYSLSS
TLTLSKADYE KHKVYACEVT HQGLSSPVTK SFNRGEC
(dimer)
(disulfide bridges: H22-H95, H147-H203, H223-L217, H229-H'229, H232-H'232, H264-H324, H370-H428, H'22-H'95, H'147-H'203, H'223-L'217, H'264-H'324, H'370-H'428, L23-L88, L137-L197, L'23-L'88, L'137-L'197)
  Type
Peptide
Efficacy
Anti-inflammatory, Antirheumatic
Comment
Monoclonal antibody
Autoimmune diseases, rheumatoid arthiritis
Other DBs
CAS: 1236278-28-6
PubChem: 163312342
LinkDB All DBs

» Japanese version   » Back

DBGET integrated database retrieval system