| Entry |
|
|---|
| Name |
Elosulfase alfa (USAN);
Elosulfase alfa (genetical recombination) (JAN);
Vimizim (TN)
|
|---|
| Product |
|
|---|
| Formula |
C5020H7588N1364O1418S34
|
|---|
| Exact mass |
110755.4086
|
|---|
| Mol weight |
110824.4607
|
|---|
| Sequence |
APQPPNILLL LMDDMGWGDL GVYGEPSRET PLCSPSRAAL LTGRLPIRNG FYTTNAHARN
LLKKAGYVSK IVGKWHLGHR PQFHPLKHGF NIPVYRDWEM VGRYYEEFPI NLKTGEANLT
FLYWAVDATH APVYASKPFL GTSQRGRYGD VADNTFVFFT SDNGAALISA PEQGGSNGPF
PGHVTAGQVS HQLGSIMDLF TTSLALAGLT LMDRPIFYYR GDTLMAATLG QHKAHFWTWT
VTTHNLEDHT KLPLIFHLGR DPGERFPLSF EALVPAQPQL NVCNWAVMNW APPGCEKLGK
PNLDRMAAEG LLFPNFYSAN AYTPQEIVGG IPDSEQLLPE DEWFGSPNCH FGPYDNKARP
QIYLQEALDF IKRQARHHPF AVREIDDSIG KILELLQDLH LCGKQTTFEG GMREPALAWW
PPSDRAIDGL NLLPTLLQGR NSWENFRQGI DFCPGQNVSG ASAEYQEALS RITSVVQQHQ
CLTPPESIPK KCLWSH
(Dimer:Disulfide bridges:139-139' 282-393 282'-393' 463-492 463'-492' 475-481 475'-481') |
|---|
| Type |
Peptide |
|---|
| Remark |
| Therapeutic category: | 3959 |
|
|---|
| Efficacy |
Enzyme replenisher |
|---|
| Disease |
Mucopolysaccharidosis type IVA [DS: H00123] |
|---|
| Comment |
Treatment of Morquio syndrome
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16AB Enzymes
A16AB12 Elosulfasealfa
D10333 Elosulfase alfa (USAN) <JP/US>
USP drug classification [BR:br08302]
Genetic or Enzyme Disorder: Replacement, Modifiers, Treatment
Elosulfase Alfa
D10333 Elosulfase alfa (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
395 Enzyme preparations
3959 Others
D10333 Elosulfase alfa (USAN); Elosulfase alfa (genetical recombination) (JAN)
New drug approvals in the USA [br08319.html]
New Molecular Entity and New Therapeutic Biological Product Approvals
D10333
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D10333
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D10333
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D10333
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and germline mutations
D10333
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| Other DBs |
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| LinkDB |
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