KEGG   DRUG: Elosulfase alfaHelp
Entry
D10333                      Drug                                   

Name
Elosulfase alfa (USAN);
Elosulfase alfa (genetical recombination) (JAN);
Vimizim (TN)
Product
Formula
C5020H7588N1364O1418S34
Exact mass
110755.4086
Mol weight
110824.4607
Sequence
APQPPNILLL LMDDMGWGDL GVYGEPSRET PLCSPSRAAL LTGRLPIRNG FYTTNAHARN
LLKKAGYVSK IVGKWHLGHR PQFHPLKHGF NIPVYRDWEM VGRYYEEFPI NLKTGEANLT
FLYWAVDATH APVYASKPFL GTSQRGRYGD VADNTFVFFT SDNGAALISA PEQGGSNGPF
PGHVTAGQVS HQLGSIMDLF TTSLALAGLT LMDRPIFYYR GDTLMAATLG QHKAHFWTWT
VTTHNLEDHT KLPLIFHLGR DPGERFPLSF EALVPAQPQL NVCNWAVMNW APPGCEKLGK
PNLDRMAAEG LLFPNFYSAN AYTPQEIVGG IPDSEQLLPE DEWFGSPNCH FGPYDNKARP
QIYLQEALDF IKRQARHHPF AVREIDDSIG KILELLQDLH LCGKQTTFEG GMREPALAWW
PPSDRAIDGL NLLPTLLQGR NSWENFRQGI DFCPGQNVSG ASAEYQEALS RITSVVQQHQ
CLTPPESIPK KCLWSH
(Dimer:Disulfide bridges:139-139' 282-393 282'-393' 463-492 463'-492' 475-481 475'-481')
  Type
Peptide
Remark
Therapeutic category: 3959
ATC code: A16AB12
Product: D10333<JP/US>
Efficacy
Enzyme replenisher
  Disease
Mucopolysaccharidosis type IVA [DS:H00123]
Comment
Treatment of Morquio syndrome
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
   A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
    A16AB Enzymes
     A16AB12 Elosulfasealfa
      D10333  Elosulfase alfa (USAN) <JP/US>
USP drug classification [BR:br08302]
 Genetic or Enzyme Disorder: Replacement, Modifiers, Treatment
  Elosulfase Alfa
   D10333  Elosulfase alfa (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   395  Enzyme preparations
    3959  Others
     D10333  Elosulfase alfa (USAN); Elosulfase alfa (genetical recombination) (JAN)
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D10333
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D10333
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D10333
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10333
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and germline mutations
  D10333
BRITE hierarchy
Other DBs
CAS: 9025-60-9
PubChem: 172232427
LinkDB All DBs

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