| Entry |
|
|---|
| Name |
Lasmiditan (USAN/INN) |
|---|
| Formula |
C19H18F3N3O2
|
|---|
| Exact mass |
377.1351
|
|---|
| Mol weight |
377.36
|
|---|
| Structure |
|
|---|
| Remark |
| Product (DG01332): | D10424<JP/US> |
|
|---|
| Efficacy |
Antimigraine, Hydroxytryptamine receptor agonist |
|---|
| Comment |
Treatment of acute migraine
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02C ANTIMIGRAINE PREPARATIONS
N02CC Selective serotonin (5HT1) agonists
N02CC08 Lasmiditan
D10338 Lasmiditan (USAN/INN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Serotonin
HTR1F
D10338 Lasmiditan (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
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|---|
| KCF data |
ATOM 27
1 C8x C 12.8800 -18.3400
2 C8y C 12.8800 -19.7400
3 C8x C 14.0924 -20.4400
4 C8y C 15.3049 -19.7400
5 C8y C 15.3049 -18.3400
6 C8y C 14.0924 -17.6400
7 X F 16.5173 -20.4400
8 N1b N 17.7297 -18.3400
9 C5a C 16.5173 -17.6400
10 C8y C 18.9273 -17.6485
11 N5x N 20.1156 -18.3345
12 C8y C 21.3280 -17.6345
13 C8x C 21.3280 -16.2345
14 C8x C 20.1397 -15.5485
15 C8x C 18.9273 -16.2485
16 C5a C 22.5404 -18.3345
17 C1y C 23.7529 -17.6345
18 C1x C 23.7529 -16.2345
19 O5a O 22.5404 -19.7400
20 C1x C 24.9653 -18.3345
21 C1x C 26.1778 -17.6346
22 N1y N 26.1778 -16.2346
23 C1x C 24.9653 -15.5345
24 C1a C 27.3895 -15.5350
25 O5a O 16.5173 -16.2400
26 X F 11.6676 -20.4400
27 X F 14.0924 -16.2402
BOND 29
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 8 9 1
9 5 9 1
10 8 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 13 14 1
15 14 15 2
16 10 15 1
17 12 16 1
18 16 17 1
19 17 18 1
20 16 19 2
21 17 20 1
22 20 21 1
23 21 22 1
24 22 23 1
25 18 23 1
26 22 24 1
27 9 25 2
28 2 26 1
29 6 27 1
|
|---|
