KEGG   DRUG: LasmiditanHelp
Entry
D10338                      Drug                                   

Name
Lasmiditan (USAN/INN)
Formula
C19H18F3N3O2
Exact mass
377.1351
Mol weight
377.3603
Structure
Mol fileKCF fileDB search
Remark
Chemical structure group: DG01332
Efficacy
Antimigraine, Hydroxytryptamine receptor agonist
Comment
Treatment of acute migraine
Target
HTR1F [HSA:3355] [KO:K04153]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    HTR1F
     D10338  Lasmiditan (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 439239-90-4
PubChem: 172232432
ChEMBL: CHEMBL3039520
LinkDB All DBs
KCF data Show

ATOM        27
            1   C8x C    12.8800  -18.3400
            2   C8y C    12.8800  -19.7400
            3   C8x C    14.0924  -20.4400
            4   C8y C    15.3049  -19.7400
            5   C8y C    15.3049  -18.3400
            6   C8y C    14.0924  -17.6400
            7   X   F    16.5173  -20.4400
            8   N1b N    17.7297  -18.3400
            9   C5a C    16.5173  -17.6400
            10  C8y C    18.9273  -17.6485
            11  N5x N    20.1156  -18.3345
            12  C8y C    21.3280  -17.6345
            13  C8x C    21.3280  -16.2345
            14  C8x C    20.1397  -15.5485
            15  C8x C    18.9273  -16.2485
            16  C5a C    22.5404  -18.3345
            17  C1y C    23.7529  -17.6345
            18  C1x C    23.7529  -16.2345
            19  O5a O    22.5404  -19.7400
            20  C1x C    24.9653  -18.3345
            21  C1x C    26.1778  -17.6346
            22  N1y N    26.1778  -16.2346
            23  C1x C    24.9653  -15.5345
            24  C1a C    27.3895  -15.5350
            25  O5a O    16.5173  -16.2400
            26  X   F    11.6676  -20.4400
            27  X   F    14.0924  -16.2402
BOND        29
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     8   9 1
            9     5   9 1
            10    8  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14   13  14 1
            15   14  15 2
            16   10  15 1
            17   12  16 1
            18   16  17 1
            19   17  18 1
            20   16  19 2
            21   17  20 1
            22   20  21 1
            23   21  22 1
            24   22  23 1
            25   18  23 1
            26   22  24 1
            27    9  25 2
            28    2  26 1
            29    6  27 1

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