KEGG   DRUG: ActoxumabHelp
Entry
D10360                      Drug                                   

Name
Actoxumab (USAN/INN)
Formula
C6476H10000N1740O2010S46
Exact mass
145776.0927
Mol weight
145866.1352
Sequence
(Heavy chain)
QVQLVESGGG VVQPGRSLRL SCAASGFSFS NYGMHWVRQA PGKGLEWVAL IWYDGSNEDY
TDSVKGRFTI SRDNSKNTLY LQMNSLRAED TAVYYCARWG MVRGVIDVFD IWGQGTVVTV
SSASTKGPSV FPLAPSSKST SGGTAALGCL VKDYFPEPVT VSWNSGALTS GVHTFPAVLQ
SSGLYSLSSV VTVPSSSLGT QTYICNVNHK PSNTKVDKRV EPKSCDKTHT CPPCPAPELL
GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ
YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR
EEMTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS
RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GK
(Light chain)
DIQMTQSPSS VSASVGDRVT ITCRASQGIS SWLAWYQHKP GKAPKLLIYA ASSLQSGVPS
RFSGSGSGTD FTLTISSLQP EDFATYYCQQ ANSFPWTFGQ GTKVEIKRTV AAPSVFIFPP
SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT
LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
(dimer; disulfide bridges: H22-H96, H149-H205, H225-L214, H231-H'231, H234-H'234, H266-H326, H372-H430, H'22-H'96, H'149-H'205, H'225-L'214, L'266-H'326, H'372-H'430, L23-L88, L134-L194, L'23-L'88, L'134-L'194)
  Type
Peptide
Efficacy
Antibacterial
Comment
Monoclonal antibody
Prevention of recurrence of Clostridium difficile infection
Other DBs
CAS: 1245634-25-6
PubChem: 172232453
LinkDB All DBs

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