KEGG   DRUG: QuilizumabHelp
Entry
D10409                      Drug                                   

Name
Quilizumab (USAN/INN)
Formula
C6492H10052N1728O2026S44
Exact mass
146044.4372
Mol weight
146134.4993
Sequence
(Heavy chain)
EVQLVESGGG LVQPGGSLRL SCAASGFTFS DYGIAWVRQA PGKGLEWVAF ISDLAYTIYY
ADTVTGRFTI SRDNSKNTLY LQMNSLRAED TAVYYCARDN WDAMDYWGQG TLVTVSSAST
KGPSVFPLAP SSKSTSGGTA ALGCLVKDYF PEPVTVSWNS GALTSGVHTF PAVLQSSGLY
SLSSVVTVPS SSLGTQTYIC NVNHKPSNTK VDKKVEPKSC DKTHTCPPCP APELLGGPSV
FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY
RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSREEMTK
NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG
NVFSCSVMHE ALHNHYTQKS LSLSPGK
(Light chain)
DIQMTQSPSS LSASVGDRVT ITCRSSQSLV HNNANTYLHW YQQKPGKAPK LLIYKVSNRF
SGVPSRFSGS GSGTDFTLTI SSLQPEDFAT YYCSQNTLVP WTFGQGTKVE IKRTVAAPSV
FIFPPSDEQL KSGTASVVCL LNNFYPREAK VQWKVDNALQ SGNSQESVTE QDSKDSTYSL
SSTLTLSKAD YEKHKVYACE VTHQGLSSPV TKSFNRGEC
(Dimer)
(Disulfide bridges: H22-H96, H144-H200, H220-L219, H226-H'226, H229-H'229, H271-H321, H367-H425, H22'-H'96, H'144-H'200, H'220-L'219, H'261-H'321, H'367-H'425, L23-L93, L139-L199, L'23-L'93, L'139-L'199)
(Glycosylation sites (N) : H297, H'297)
  Type
Peptide
Efficacy
Antiasthmatic
Comment
Monoclonal antibody
Treatment of asthma
Other DBs
CAS: 1228538-47-3
PubChem: 172232502
LinkDB All DBs

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