KEGG   DRUG: Latanoprostene bunodHelp
Entry
D10441                      Drug                                   

Name
Latanoprostene bunod (USAN/INN)
Product
Formula
C27H41NO8
Exact mass
507.2832
Mol weight
507.6163
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Other
 DG01961  Prostaglandin derivative
  DG01960  Prostaglandin F derivative
 DG02573  Prostanoid derivative
  DG01961  Prostaglandin derivative
   DG01960  Prostaglandin F derivative
Remark
Product: D10441<US>
Efficacy
Antiglaucoma, Prostaglandin F receptor agonist
Comment
prostaglandin F2-alpha [DR:D00081] derivative
Target
PTGFR [HSA:5737] [KO:K04262]
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Prostaglandin
    PTGFR
     D10441  Latanoprostene bunod (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D10441
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10441
BRITE hierarchy
Other DBs
CAS: 860005-21-6
PubChem: 172232534
ChEMBL: CHEMBL2364612
LinkDB All DBs
KCF data Show

ATOM        36
            1   C1y C    10.6293  -14.0559
            2   C1y C    10.6293  -15.4590
            3   C1y C     9.2262  -13.6349
            4   C1b C    11.8220  -13.3543
            5   C1y C     9.2963  -15.8799
            6   C1b C    11.8220  -16.1606
            7   C1x C     8.4545  -14.7574
            8   C2b C    13.0147  -14.0559
            9   O1a O     8.8754  -17.2831
            10  C1b C    13.0147  -15.4590
            11  C1c C    14.2775  -16.1606
            12  C1b C    15.4701  -15.4590
            13  O1a O    14.2775  -17.5637
            14  C1b C    16.7330  -16.1606
            15  C8y C    16.7330  -17.5637
            16  C8x C    17.9256  -18.2653
            17  C8x C    17.9256  -19.6684
            18  C8x C    16.7330  -20.3700
            19  C8x C    15.4701  -19.6684
            20  C8x C    15.4701  -18.2653
            21  O1a O     8.7351  -12.3019
            22  C2b C    14.4178  -14.0559
            23  C1b C    15.6105  -13.3543
            24  C1b C    16.8031  -14.0559
            25  C1b C    17.9958  -13.3543
            26  C7a C    19.1885  -14.0559
            27  O7a O    20.3811  -13.3543
            28  C1b C    21.5738  -14.0559
            29  C1b C    22.7665  -13.3543
            30  O6a O    19.1885  -15.4590
            31  C1b C    23.9873  -14.0459
            32  C1b C    25.1713  -13.3493
            33  O2a O    26.3795  -14.0338
            34  N2b N    27.5533  -13.3434 #+
            35  O3a O    28.7664  -14.0309 #-
            36  O3a O    27.6120  -11.9512
BOND        37
            1    12  14 1
            2     5   7 1
            3    14  15 1
            4     1   2 1
            5     1   3 1
            6     1   4 1 #Down
            7     2   5 1
            8     2   6 1 #Up
            9    15  16 2
            10   16  17 1
            11   17  18 2
            12   18  19 1
            13   19  20 2
            14   20  15 1
            15    3   7 1
            16    4   8 1
            17    5   9 1 #Down
            18    6  10 1
            19   10  11 1
            20   11  12 1
            21   11  13 1 #Down
            22    3  21 1 #Down
            23    8  22 2
            24   23  24 1
            25   23  22 1
            26   24  25 1
            27   25  26 1
            28   26  27 1
            29   27  28 1
            30   28  29 1
            31   26  30 2
            32   29  31 1
            33   31  32 1
            34   32  33 1
            35   33  34 1
            36   34  35 1
            37   34  36 2

» Japanese version   » Back

DBGET integrated database retrieval system