KEGG   DRUG: Sodium zirconium cyclosilicateHelp
Entry
D10727                      Drug                                   

Name
Sodium zirconium cyclosilicate (USAN)
Product
Formula
ZrH4O6. 3H4SiO4. 2H2O. 2Na
Exact mass
559.8698
Mol weight
561.6068
Structure
Mol fileKCF fileDB search
Remark
ATC code: V03AE10
Product: D10727<US>
Efficacy
Antihyperkalemic
Comment
selective cation exchanger
Treatment of hyperkalemia
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 V VARIOUS
  V03 ALL OTHER THERAPEUTIC PRODUCTS
   V03A ALL OTHER THERAPEUTIC PRODUCTS
    V03AE Drugs for treatment of hyperkalemia and hyperphosphatemia
     V03AE10 Sodium zirconium cyclosilicate
      D10727  Sodium zirconium cyclosilicate (USAN)
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D10727
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D10727
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10727
BRITE hierarchy
Other DBs
CAS: 242800-27-7
PubChem: 254741688
LinkDB All DBs
KCF data Show

ATOM        26
            1   Z   Si   15.2121  -14.7857
            2   O1a O    15.2121  -13.4041
            3   O1a O    15.2121  -16.1673
            4   O1a O    16.5937  -14.7857
            5   O1a O    13.8306  -14.7857
            6   Z   Zr   22.8109  -14.5785
            7   O1a O    23.5016  -13.3820
            8   O1a O    22.1201  -13.3820 #-
            9   O1a O    21.4293  -14.5785
            10  O1a O    24.1924  -14.5785
            11  O1a O    21.9721  -15.9007
            12  O1a O    23.5016  -15.7749 #-
            13  O0  O    23.7770  -18.7306
            14  Z   Na   21.6300  -11.8300 #+
            15  Z   Na   24.5700  -16.5900 #+
            16  Z   Si   15.2121  -14.7857
            17  O1a O    15.2121  -13.4041
            18  O1a O    15.2121  -16.1673
            19  O1a O    16.5937  -14.7857
            20  O1a O    13.8306  -14.7857
            21  Z   Si   15.2121  -14.7857
            22  O1a O    15.2121  -13.4041
            23  O1a O    15.2121  -16.1673
            24  O1a O    16.5937  -14.7857
            25  O1a O    13.8306  -14.7857
            26  O0  O    23.7770  -18.7306
BOND        18
            1     6   7 1
            2     6   8 1
            3     6   9 1
            4     6  10 1
            5     6  11 1
            6     6  12 1
            7     1   2 1
            8     1   3 1
            9     1   4 1
            10    1   5 1
            11   16  17 1
            12   16  18 1
            13   16  19 1
            14   16  20 1
            15   21  22 1
            16   21  23 1
            17   21  24 1
            18   21  25 1
BRACKET     1    12.6700  -16.5900   12.6700  -12.6700
            1    17.7800  -12.6700   17.7800  -16.5900
            1  3
 ORIGINAL  1    1   2   3   4   5
 REPEAT    1   16  17  18  19  20  21  22  23  24  25
            2    22.1200  -19.6700   22.1200  -18.0600
            2    24.2900  -18.0600   24.2900  -19.6700
            2  2
 ORIGINAL  2   13
 REPEAT    2   26

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