KEGG   DRUG: Alipogene tiparvovecHelp
Entry
D10843                      Drug                                   

Name
Alipogene tiparvovec (INN);
Glybera (TN)
Remark
ATC code: C10AX10
Efficacy
Antihyperlipidemic
  Disease
Lipoprotein lipase deficiency (LPL S447X variant) [DS:H00154]
Comment
Gene therapy product
Adeno-associated virus serotype 1 (AAV1) vector carrying LPL [HSA:4023]
Target
LPL [HSA_VAR:4023v1] [HSA:4023] [KO:K01059]
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C10 LIPID MODIFYING AGENTS
   C10A LIPID MODIFYING AGENTS, PLAIN
    C10AX Other lipid modifying agents
     C10AX10 Alipogene tiparvovec
      D10843  Alipogene tiparvovec (INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Carboxylic-ester hydrolases
    LPL [HSA_VAR:4023v1]
     D10843  Alipogene tiparvovec (INN)
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D10843
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10843
BRITE hierarchy
Other DBs
CAS: 929881-05-0
PubChem: 319902643
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