KEGG   DRUG: CrisaboroleHelp
Entry
D10873                      Drug                                   

Name
Crisaborole (USAN/INN);
Eucrisa (TN)
Product
Formula
C14H10BNO3
Exact mass
251.0754
Mol weight
251.0451
Structure
Mol fileKCF fileDB search
Remark
Product: D10873<US>
Efficacy
Antipsoriatic, Phosphodiesterase inhibitor
  Disease
Atopic dermatitis [DS:H01358]
Target
PDE4 [HSA:5141 5142 5143 5144] [KO:K13293]
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Phosphodiesterase
    PDE4
     D10873  Crisaborole (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D10873
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10873
BRITE hierarchy
Other DBs
CAS: 906673-24-3
PubChem: 319902673
ChEBI: 134677
ChEMBL: CHEMBL484785
LinkDB All DBs
KCF data Show

ATOM        19
            1   C8x C    16.9311  -16.0216
            2   C8y C    16.9311  -17.4208
            3   C8x C    18.1205  -18.1205
            4   C8y C    19.3798  -17.4208
            5   C8y C    19.3798  -16.0216
            6   C8x C    18.1205  -15.3219
            7   O2a O    15.7417  -18.1205
            8   C1x C    20.7091  -17.8406
            9   O2x O    21.5487  -16.7212
            10  Z   B    20.7091  -15.6018
            11  O1a O    21.1289  -14.2725
            12  C8y C    14.5340  -17.4362
            13  C8x C    14.5924  -16.0305
            14  C8x C    13.3043  -15.3405
            15  C8y C    12.0976  -16.0505
            16  C8x C    12.1092  -17.4562
            17  C8x C    13.3273  -18.1462
            18  C3b C    10.8803  -15.3609
            19  N3a N     9.6678  -14.6609
BOND        21
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     2   7 1
            8     4   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12   10  11 1
            13    7  12 1
            14   12  13 2
            15   13  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 2
            19   12  17 1
            20   15  18 1
            21   18  19 3

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