KEGG   DRUG: Pegteograstim
Entry
D11026                      Drug                                   
Name
Pegteograstim (INN)
Sequence
MTPLGPASSL PQSFLLKSLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA
PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ
QMEELGMAPA LQPTQGCAMP AFASAFQRRA GGVLVASHLQ SFLEVSYRVL RHLAQP
(Disulfide bridge: 37-43, 65-75)
  Type
Peptide
Class
Immunological agent
 DG01753  Colony stimulating factor
  DG01781  Granulocyte colony stimulating factor (G-CSF)
Remark
ATC code: L03AA17
Efficacy
Antineutropenic, Granulocyte colony stimulating factor (G-CSF)
Target
CSF3R (GCSFR, CD114) [HSA:1441] [KO:K05061]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04151  PI3K-Akt signaling pathway
hsa04630  JAK-STAT signaling pathway
hsa04640  Hematopoietic cell lineage
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AA Colony stimulating factors
     L03AA17 Pegteograstim
      D11026  Pegteograstim (INN)
Drug groups [BR:br08330]
 Immunological agent
  DG01753  Colony stimulating factor
   DG01781  Granulocyte colony stimulating factor (G-CSF)
    D11026  Pegteograstim
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   CSF and other factor receptors
    CSF3R (GCSFR, CD114)
     D11026  Pegteograstim (INN)
Other DBs
CAS: 1329602-23-4
PubChem: 350078345
LinkDB

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