| Entry |
|
|---|
| Name |
Levothyroxine sodium (INN);
Levothyroxine sodium anhydrous |
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| Product |
|
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| Generic |
|
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| Formula |
C15H10I4NO4. Na
|
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| Exact mass |
798.6686
|
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| Mol weight |
798.85
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Hormonal agent
DG01953 Thyroid preparation
DG01608 Thyroid hormone replenisher
|
|---|
| Remark |
| Product (DG00510): | D01010<JP/US> D11113<US> |
|
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| Efficacy |
Replenisher (thyroid hormone) |
|---|
| Comment |
Treatment of myxedema coma
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04919 | Thyroid hormone signaling pathway |
|
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| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H03 THYROID THERAPY
H03A THYROID PREPARATIONS
H03AA Thyroid hormones
H03AA01 Levothyroxine sodium
D11113 Levothyroxine sodium (INN) <US>
USP drug classification [BR:br08302]
Hormonal Agents, Stimulant/Replacement/Modifying (Thyroid)
Levothyroxine
D11113 Levothyroxine sodium (INN)
Drug groups [BR:br08330]
Hormonal agent
DG01953 Thyroid preparation
DG01608 Thyroid hormone replenisher
DG00510 Levothyroxine
D11113 Levothyroxine sodium
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Thyroid hormone receptor (THR)
NR1A (THR)
D11113 Levothyroxine sodium (INN) <US>
Drug groups [BR:br08330]
Hormonal agent
DG01953 Thyroid preparation
DG01608 Thyroid hormone replenisher
DG00510 Levothyroxine
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 25
1 C8y C 23.1126 -16.8804
2 O2a O 21.9219 -16.1800
3 C8x C 23.1126 -18.2813
4 C8x C 24.3734 -16.1800
5 C8y C 20.7311 -15.4795
6 C8y C 24.3734 -18.9817
7 C8y C 25.5641 -16.8804
8 C8y C 19.5404 -16.1800
9 C8y C 20.7311 -14.0787
10 C8y C 25.5641 -18.2813
11 X I 24.3734 -20.3826
12 X I 26.7548 -16.1099
13 C8x C 18.2796 -15.4795
14 X I 19.5404 -17.5808
15 C8x C 19.5404 -13.3782
16 X I 21.9219 -13.3782
17 O1a O 26.8249 -18.9116
18 C8y C 18.2796 -14.0787
19 C1b C 17.0889 -13.3782
20 C1c C 15.8982 -14.0787
21 C6a C 14.7074 -13.3782
22 N1a N 15.8982 -15.4795
23 O6a O 14.7074 -11.9774
24 O6a O 13.5167 -14.0787 #-
25 Z Na 10.4348 -14.1487 #+
BOND 25
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 3 6 1
6 4 7 2
7 5 8 1
8 5 9 2
9 6 10 2
10 6 11 1
11 7 12 1
12 8 13 2
13 8 14 1
14 9 15 1
15 9 16 1
16 10 17 1
17 13 18 1
18 18 19 1
19 19 20 1
20 20 21 1
21 20 22 1 #Down
22 21 23 2
23 21 24 1
24 7 10 1
25 15 18 2
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