| Entry |
|
|---|
| Name |
Lesinidase alfa (USAN/INN) |
|---|
| Formula |
C3660H5527N991O1018S20
|
|---|
| Exact mass |
80289.5598
|
|---|
| Mol weight |
80339.41
|
|---|
| Sequence |
DEAREAAAVR ALVARLLGPG PAADFSVSVE RALAAKPGLD TYSLGGGGAA RVRVRGSTGV
AAAAGLHRYL RDFCGCHVAW SGSQLRLPRP LPAVPGELTE ATPNRYRYYQ NVCTQSYSFV
WWDWARWERE IDWMALNGIN LALAWSGQEA IWQRVYLALG LTQAEINEFF TGPAFLAWGR
MGNLHTWDGP LPPSWHIKQL YLQHRVLDQM RSFGMTPVLP AFAGHVPEAV TRVFPQVNVT
KMGSWGHFNC SYSCSFLLAP EDPIFPIIGS LFLRELIKEF GTDHIYGADT FNEMQPPSSE
PSYLAAATTA VYEAMTAVDT EAVWLLQGWL FQHQPQFWGP AQIRAVLGAV PRGRLLVLDL
FAESQPVYTR TASFQGQPFI WCMLHNFGGN HGLFGALEAV NGGPEAARLF PNSTMVGTGM
APEGISQNEV VYSLMAELGW RKDPVPDLAA WVTSFAARRY GVSHPDAGAA WRLLLRSVYN
CSGEACRGHN RSPLVRRPSL QMNTSIWYNR SDVFEAWRLL LTSAPSLATS PAFRYDLLDL
TRQAVQELVS LYYEEARSAY LSKELASLLR AGGVLAYELL PALDEVLASD SRFLLGSWLE
QARAAAVSEA EADFYEQNSR YQLTLWGPEG NILDYANKQL AGLVANYYTP RWRLFLEALV
DSVAQGIPFQ QHQFDKNVFQ LEQAFVLSKQ RYPSQPRGDT VDLAKKIFLK YYPRWVAGS
(Disulfide bridge: 250-254, 481-486) |
|---|
| Type |
Peptide |
|---|
| Efficacy |
Lysosomal storage disease treatment, Enzyme replacement (alpha-N-acetylglucosaminidase) |
|---|
| Type |
Enzyme replacement therapy product |
|---|
| Comment |
Treatment of mucopolysaccharidosis IIIB
|
|---|
| Target |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Glycosidases
NAGLU* [HSA_VAR:4669v1]
D11199 Lesinidase alfa (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
