KEGG   DRUG: Molidustat sodium
Entry
D11273                      Drug                                   
Name
Molidustat sodium (JAN/USAN);
Musredo (TN)
Formula
C13H13N8O2. Na
Exact mass
336.1059
Mol weight
336.28
Structure
Remark
Therapeutic category: 3999
ATC code: B03XA09
Chemical structure group: DG03157
Product (DG03157): D11273<JP>
Efficacy
Anti-anemic, Hypoxia inducible factor-prolyl hydroxylase (HIF-PH) inhibitor
Comment
Management of anemia associated with chronic kidney disease in cats
Target
EGLN (HPH) [HSA:54583 112398 112399] [KO:K09592]
  Pathway
hsa04066  HIF-1 signaling pathway
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B03 ANTIANEMIC PREPARATIONS
   B03X OTHER ANTIANEMIC PREPARATIONS
    B03XA Other antianemic preparations
     B03XA09 Molidustat
      D11273  Molidustat sodium (JAN/USAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   399  Miscellaneous
    3999  Others
     D11273  Molidustat sodium (JAN/USAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   HIF hydroxylase
    EGLN (HPH)
     D11273  Molidustat sodium (JAN/USAN) <JP>
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D11273
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11273
Other DBs
CAS: 1375799-59-9
PubChem: 384585251
LinkDB
KCF data

ATOM        24
            1   C8y C    16.0300  -20.9300
            2   N5x N    16.0300  -22.3300
            3   C8x C    17.2424  -23.0300
            4   N5x N    18.4549  -22.3300
            5   C8y C    18.4549  -20.9300
            6   C8x C    17.2424  -20.2300
            7   N1y N    19.6860  -20.2190
            8   C1x C    20.8912  -20.9147
            9   C1x C    22.1035  -20.2146
            10  O2x O    22.1035  -18.8146
            11  C1x C    20.8983  -18.1189
            12  C1x C    19.6859  -18.8190
            13  N4y N    14.8176  -20.2300
            14  C8y C    14.8304  -18.8300
            15  C8y C    13.5053  -18.3861
            16  C8x C    12.6736  -19.5092
            17  N5x N    13.4847  -20.6472
            18  O1a O    15.9768  -18.0129 #-
            19  N4y N    13.0920  -17.0739
            20  C8x C    13.9215  -15.9537
            21  C8x C    13.1124  -14.8186
            22  N5x N    11.7830  -15.2373
            23  N5x N    11.7703  -16.6311
            24  Z   Na   15.7500  -15.8200 #+
BOND        26
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13    7  12 1
            14    1  13 1
            15   13  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 2
            19   13  17 1
            20   14  18 1
            21   15  19 1
            22   19  20 1
            23   21  22 1
            24   22  23 2
            25   19  23 1
            26   20  21 2

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