| Entry |
|
|---|
| Name |
Pimodivir (USAN/INN) |
|---|
| Formula |
C20H19F2N5O2
|
|---|
| Exact mass |
399.1507
|
|---|
| Mol weight |
399.394
|
|---|
| Structure |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiviral |
|---|
| Comment |
Treatment of influenza A
|
|---|
| Target |
Influenza polymerase basic protein 2 [KO: K19388] |
|---|
| Pathway |
|
|---|
| Brite |
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Other inhibitor
D11287 Pimodivir (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 29
1 C8x C 13.0136 -14.2217
2 C8y C 13.0136 -15.6357
3 C8x C 14.2154 -16.3427
4 C8y C 15.4880 -15.6357
5 C8y C 15.4880 -14.2217
6 N5x N 14.2154 -13.5147
7 X F 11.8117 -16.3427
8 C8y C 16.8313 -16.0599
9 C8x C 17.6090 -14.9287
10 N4x N 16.8313 -13.7975
11 C8y C 18.0332 -16.7669
12 N5x N 18.0332 -18.1809
13 C8x C 19.2351 -18.8879
14 C8y C 20.5077 -18.1809
15 C8y C 20.5077 -16.7669
16 N5x N 19.2351 -16.0599
17 X F 21.7263 -18.8980
18 N1b N 21.7263 -16.0498
19 C1y C 22.9481 -16.7420
20 C1y C 22.9593 -18.1807
21 C1x C 24.1893 -18.8782
22 C1x C 25.4084 -18.1617
23 C1y C 25.3971 -16.7231
24 C1y C 24.1672 -16.0256
25 C6a C 24.1569 -14.6462
26 O6a O 22.9477 -13.9598
27 O6a O 25.3963 -13.9181
28 C1x C 24.0313 -16.9476
29 C1x C 24.3251 -17.9562
BOND 33
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 2 7 1
8 4 8 1
9 8 9 2
10 9 10 1
11 5 10 1
12 11 12 2
13 12 13 1
14 13 14 2
15 14 15 1
16 15 16 2
17 11 16 1
18 11 8 1
19 14 17 1
20 15 18 1
21 19 18 1 #Down
22 19 20 1
23 20 21 1
24 21 22 1
25 22 23 1
26 23 24 1
27 19 24 1
28 24 25 1 #Up
29 25 26 2
30 25 27 1
31 23 28 1
32 20 29 1
33 29 28 1
|
|---|
