| Entry |
|
|---|
| Name |
Rislenemdaz (USAN) |
|---|
| Formula |
C19H23FN4O2
|
|---|
| Exact mass |
358.1805
|
|---|
| Mol weight |
358.41
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
|
|---|
| Efficacy |
Antidepressant, NMDA receptor antagonist |
|---|
| Comment |
Treatment of major depressive disorder
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
D11340 Rislenemdaz
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Glutamate (ionotropic), NMDA
GRIN2B (NMDAR2B)
D11340 Rislenemdaz (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 26
1 C8x C 7.7700 -15.6800
2 C8x C 7.7700 -17.0800
3 C8x C 8.9824 -17.7800
4 N5x N 10.1949 -17.0800
5 C8y C 10.1949 -15.6800
6 N5x N 8.9824 -14.9800
7 N1b N 11.4260 -14.9690
8 C1b C 12.6312 -15.6647
9 C1y C 13.8135 -14.9819
10 C1x C 15.0075 -15.6712
11 C1x C 16.2199 -14.9712
12 N1y N 16.2199 -13.5712
13 C1x C 15.0260 -12.8819
14 C1y C 13.8135 -13.5819
15 C7a C 17.4434 -12.8646
16 O7a O 18.6524 -13.5625
17 O6a O 17.4432 -11.4801
18 C1b C 19.8329 -12.8808
19 C8y C 21.0278 -13.5707
20 C8x C 21.0279 -14.9797
21 C8x C 22.2404 -15.6796
22 C8y C 23.4528 -14.9795
23 C8x C 23.4526 -13.5704
24 C8x C 22.2401 -12.8706
25 C1a C 24.6634 -15.6783
26 X F 12.5827 -12.8711
BOND 28
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 9 8 1 #Down
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 9 14 1
16 12 15 1
17 15 16 1
18 15 17 2
19 16 18 1
20 18 19 1
21 19 20 2
22 20 21 1
23 21 22 2
24 22 23 1
25 23 24 2
26 19 24 1
27 22 25 1
28 14 26 1 #Down
|
|---|
