| Entry |
|
|---|
| Name |
Dorzagliatin (USAN) |
|---|
| Formula |
C22H27ClN4O5
|
|---|
| Exact mass |
462.1670
|
|---|
| Mol weight |
462.92
|
|---|
| Structure |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidiabetic, Glucokinase activator |
|---|
| Comment |
Treatment of type 2 diabetes
|
|---|
| Target |
|
|---|
| Pathway |
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|---|
| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A10 DRUGS USED IN DIABETES
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
A10BX Other blood glucose lowering drugs, excl. insulins
A10BX18 Dorzagliatin
D11342 Dorzagliatin (USAN)
Target-based classification of drugs [BR:br08310]
Enzymes
Transferases (EC2)
Phosphotransferase
GCK
D11342 Dorzagliatin (USAN)
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 32
1 C8x C 5.7400 -17.1500
2 C8x C 5.7400 -18.5500
3 C8x C 6.9300 -19.2500
4 C8y C 8.1900 -18.5500
5 C8y C 8.1900 -17.1500
6 C8x C 6.9300 -16.4500
7 O2a O 9.3800 -16.4500
8 C2y C 10.5700 -17.1500
9 X Cl 9.3800 -19.2500
10 C2x C 11.0600 -18.4800
11 C5x C 12.4600 -18.4800
12 N1y N 12.8800 -17.1500
13 C1x C 11.7600 -16.3100
14 C1c C 14.0700 -16.4500
15 C5a C 15.2600 -17.1500
16 C1b C 14.0700 -15.0500
17 C1c C 15.2600 -14.3500
18 C1a C 16.4500 -15.0500
19 C1a C 15.2600 -12.9500
20 N1b N 16.4500 -16.4500
21 C8y C 17.6400 -17.1500
22 O5a O 15.2600 -18.5500
23 C8x C 18.0600 -18.4800
24 C8x C 19.4600 -18.4800
25 N4y N 19.8800 -17.1500
26 N5x N 18.8300 -16.3800
27 O5x O 13.3000 -19.6000
28 C1b C 21.0700 -16.4500
29 C1c C 22.2600 -17.1500
30 C1b C 23.4500 -16.4500
31 O1a O 24.6400 -17.1500
32 O1a O 22.2600 -18.5500
BOND 34
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 4 9 1
10 8 10 2
11 10 11 1
12 11 12 1
13 12 13 1
14 8 13 1
15 14 15 1
16 14 12 1
17 14 16 1 #Up
18 16 17 1
19 17 18 1
20 17 19 1
21 15 20 1
22 20 21 1
23 15 22 2
24 21 23 1
25 23 24 2
26 24 25 1
27 25 26 1
28 21 26 2
29 11 27 2
30 28 29 1
31 28 25 1
32 29 30 1
33 30 31 1
34 29 32 1 #Down
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