| Entry |
|
|---|
| Name |
Reldesemtiv (USAN) |
|---|
| Formula |
C19H18F2N6O
|
|---|
| Exact mass |
384.1510
|
|---|
| Mol weight |
384.38
|
|---|
| Structure |
|
|---|
| Efficacy |
Troponin activator |
|---|
| Comment |
Treatment of muscle weakness and/or fatigue
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Not elsewhere classified
Cellular process
Cytoskeleton
TNNC2
D11363 Reldesemtiv (USAN)
TNNI2
D11363 Reldesemtiv (USAN)
TNNT3
D11363 Reldesemtiv (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 28
1 C8x C 8.6100 -13.7200
2 C8x C 8.6100 -15.1200
3 C8x C 9.8000 -15.8200
4 C8y C 11.0600 -15.1200
5 C8y C 11.0600 -13.7200
6 N5x N 9.8000 -13.0200
7 X F 12.2500 -15.8200
8 C1z C 12.2500 -13.0200
9 C1b C 13.4400 -13.7200
10 C1x C 13.2300 -12.0400
11 C1y C 12.2500 -11.0600
12 C1x C 11.2700 -12.0400
13 N1b N 14.6581 -13.0299
14 C8y C 15.8395 -13.7250
15 N5x N 15.8280 -15.1200
16 C8x C 17.0346 -15.8300
17 C8y C 18.2528 -15.1400
18 C8x C 18.2643 -13.7450
19 N5x N 17.0577 -13.0350
20 N4y N 19.4603 -15.8525
21 C8x C 19.4682 -17.2200
22 C8x C 20.7712 -17.6351
23 C8y C 21.5686 -16.5241
24 C8x C 20.7584 -15.4224
25 C5a C 22.9767 -16.5161
26 N1a N 23.6809 -17.7201
27 O5a O 23.6639 -15.3098
28 X F 13.2399 -10.0701
BOND 31
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 8 5 1 #Down
9 8 9 1 #Up
10 8 10 1
11 10 11 1
12 11 12 1
13 8 12 1
14 9 13 1
15 13 14 1
16 14 15 2
17 15 16 1
18 16 17 2
19 17 18 1
20 18 19 2
21 14 19 1
22 17 20 1
23 20 21 1
24 21 22 2
25 22 23 1
26 23 24 2
27 20 24 1
28 23 25 1
29 25 26 1
30 25 27 2
31 11 28 1 #Up
|
|---|
