KEGG   DRUG: Tisagenlecleucel-T
Entry
D11386                      Drug                                   
Name
Tisagenlecleucel-T (USAN);
Tisagenlecleucel (INN);
Kymriah (TN)
Product
Remark
ATC code: L01XL04
Product: D11386<US>
Efficacy
Antineoplastic, Anti-CD19 CAR-T cell
  Disease
B-cell acute lymphoblastic leukemia [DS:H00001]
  Type
Cellular therapy product, CAR-T cell therapy
Target
CD19 [HSA:930] [KO:K06465]
  Pathway
hsa04640  Hematopoietic cell lineage
hsa04662  B cell receptor signaling pathway
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XL Antineoplastic cell and gene therapy
     L01XL04 Tisagenlecleucel
      D11386  Tisagenlecleucel-T (USAN) <US>
Target-based classification of drugs [BR:br08310]
 Cell surface molecules and ligands
  Other cell surface molecules
   CD molecules
    CD19
     D11386  Tisagenlecleucel-T (USAN) <US>
New drug approvals in the USA [br08319.html]
 Cellular and gene therapy products
  D11386
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D11386
 Cellular and gene therapy products
  D11386
New drug approvals in Japan [br08318.html]
 Cellular and gene therapy products
  D11386
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11386
Pharmacogenomic biomarkers [br08341.html]
 Somatic variations in targeted cancer therapies
  D11386
Other DBs
CAS: 1823078-37-0
PubChem: 384585364
LinkDB

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