KEGG   DRUG: Lucerastat
Entry
D11439                      Drug                                   

Name
Lucerastat (JAN/USAN/INN)
Formula
C10H21NO4
Exact mass
219.1471
Mol weight
219.278
Structure
Simcomp
Efficacy
Glucosylceramide synthase inhibitor
Comment
Treatment of Fabry disease
Target
UGCG [HSA:7357] [KO:K00720]
  Pathway
hsa00600  Sphingolipid metabolism
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Transferases (EC2)
   Hexosyltransferases
    UGCG
     D11439  Lucerastat (JAN/USAN/INN)
Other DBs
CAS: 141206-42-0
PubChem: 384585416
ChEMBL: CHEMBL1086997
LinkDB
KCF data

ATOM        15
            1   C1y C    11.0778  -21.2631
            2   C1y C    12.3010  -21.9441
            3   C1y C    13.5024  -21.2253
            4   C1x C    13.4806  -19.8255
            5   N1y N    12.2574  -19.1445
            6   C1y C    11.0560  -19.8633
            7   O1a O    14.7255  -21.9062
            8   O1a O    12.3229  -23.3439
            9   O1a O     9.8765  -21.9819
            10  C1b C     9.8330  -19.1823
            11  O1a O     8.6148  -19.9110
            12  C1b C    12.2351  -17.7229
            13  C1b C    13.4291  -17.0084
            14  C1b C    14.6613  -17.6943
            15  C1a C    15.8327  -16.9933
BOND        15
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     3   7 1 #Down
            8     2   8 1 #Up
            9     1   9 1 #Up
            10    6  10 1 #Up
            11   10  11 1
            12    5  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1

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