| Entry |
|
|---|
| Name |
Difenoxin hydrochloride |
|---|
| Formula |
C28H28N2O2. HCl
|
|---|
| Exact mass |
460.1918
|
|---|
| Mol weight |
460.99
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
|
|---|
| Remark |
| Product (mixture): | D02128<US> |
|
|---|
| Efficacy |
Antidiarrheal, Antiperistaltic, Opioid receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07D ANTIPROPULSIVES
A07DA Antipropulsives
A07DA04 Difenoxin
D11583 Difenoxin hydrochloride
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG03054 Difenoxin
D11583 Difenoxin hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D11583 Difenoxin hydrochloride
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG03054 Difenoxin
|
|---|
| Other DBs |
|
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| LinkDB |
|
|---|
| KCF data |
ATOM 33
1 C1d C 18.6053 -19.3074
2 C8y C 17.4820 -20.0095
3 C8y C 19.7989 -20.0095
4 C1b C 18.6053 -17.9735
5 C3b C 17.1310 -18.4649
6 C8x C 17.4820 -21.3434
7 C8x C 16.2885 -19.3074
8 C8x C 19.7989 -21.3434
9 C8x C 20.9924 -19.3074
10 C1b C 19.7287 -17.2714
11 N3a N 15.5864 -17.6224
12 C8x C 16.2885 -22.0455
13 C8x C 15.0949 -20.0095
14 C8x C 20.9924 -22.0455
15 C8x C 22.1859 -20.0095
16 N1y N 19.7287 -15.8672
17 C8x C 15.0949 -21.3434
18 C8x C 22.1859 -21.3434
19 C1x C 20.9222 -15.2353
20 C1x C 18.6053 -15.2353
21 C1x C 20.9222 -13.8312
22 C1x C 18.6053 -13.8312
23 C1z C 19.7287 -13.1993
24 C6a C 20.9924 -12.4270
25 C8y C 18.5351 -12.4270
26 C8x C 18.5351 -11.0229
27 C8x C 17.2714 -10.3208
28 C8x C 16.0778 -11.0229
29 C8x C 16.0778 -12.4270
30 C8x C 17.2714 -13.1993
31 O6a O 22.1859 -13.1993
32 O6a O 20.9924 -11.0229
33 X Cl 22.9600 -17.7100
BOND 35
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 1
6 2 7 2
7 3 8 2
8 3 9 1
9 4 10 1
10 5 11 3
11 6 12 2
12 7 13 1
13 8 14 1
14 9 15 2
15 10 16 1
16 12 17 1
17 14 18 2
18 16 19 1
19 16 20 1
20 19 21 1
21 20 22 1
22 21 23 1
23 13 17 2
24 15 18 1
25 22 23 1
26 23 24 1
27 23 25 1
28 25 26 2
29 26 27 1
30 27 28 2
31 28 29 1
32 29 30 2
33 25 30 1
34 24 31 1
35 24 32 2
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