| Entry |
|
|---|
| Name |
Leriglitazone (USAN/INN);
1-Hydroxypioglitazone |
|---|
| Formula |
C19H20N2O4S
|
|---|
| Exact mass |
372.1144
|
|---|
| Mol weight |
372.44
|
|---|
| Structure |
|
|---|
| Class |
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
DG01683 Thiazolidinedione type PPAR agonist
DG02044 Hypoglycemic agent
DG01683 Thiazolidinedione type PPAR agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Peroxisome proliferator-activated receptor (PPAR) gamma agonist |
|---|
| Comment |
Treatment of X-linked adrenoleukodystrophy
|
|---|
| Target |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16AX Various alimentary tract and metabolism products
A16AX23 Leriglitazone
D11603 Leriglitazone (USAN/INN)
Drug groups [BR:br08330]
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
DG01683 Thiazolidinedione type PPAR agonist
DG03060 Leriglitazone
D11603 Leriglitazone
DG02044 Hypoglycemic agent
DG01683 Thiazolidinedione type PPAR agonist
DG03060 Leriglitazone
D11603 Leriglitazone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
NR1C3 (PPARG)
D11603 Leriglitazone (USAN/INN)
Drug groups [BR:br08330]
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
DG01683 Thiazolidinedione type PPAR agonist
DG03060 Leriglitazone
DG02044 Hypoglycemic agent
DG01683 Thiazolidinedione type PPAR agonist
DG03060 Leriglitazone
|
|---|
| Other DBs |
|
|---|
| LinkDB |
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|---|
| KCF data |
ATOM 26
1 C1y C 24.1232 -15.3821
2 C1b C 22.9346 -14.6829
3 C5x C 24.1232 -16.7805
4 S2x S 25.4517 -14.9626
5 C8y C 21.7460 -15.3821
6 N1x N 25.4517 -17.2000
7 O5x O 23.0045 -17.6195
8 C5x C 26.2907 -16.0813
9 C8x C 20.4875 -14.6829
10 C8x C 21.7460 -16.7805
11 O5x O 27.6891 -16.0813
12 C8x C 19.2989 -15.3821
13 C8x C 20.4875 -17.4797
14 C8y C 19.2989 -16.7805
15 O2a O 18.1102 -17.4797
16 C1b C 16.8517 -16.7805
17 C1b C 15.6631 -17.4797
18 C8y C 14.4745 -16.7805
19 C8x C 14.4745 -15.3821
20 N5x N 13.2159 -17.4797
21 C8x C 13.2159 -14.6829
22 C8x C 12.0273 -16.7805
23 C8y C 12.0273 -15.3821
24 C1c C 10.8387 -14.6829
25 C1a C 9.5802 -15.3821
26 O1a O 10.8559 -13.3000
BOND 28
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 1
6 3 7 2
7 4 8 1
8 5 9 2
9 5 10 1
10 8 11 2
11 9 12 1
12 10 13 2
13 12 14 2
14 14 15 1
15 15 16 1
16 16 17 1
17 17 18 1
18 18 19 2
19 18 20 1
20 19 21 1
21 20 22 2
22 21 23 2
23 23 24 1
24 24 25 1
25 6 8 1
26 13 14 1
27 22 23 1
28 24 26 1
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