| Entry |
|
|---|
| Name |
Leriglitazone (USAN/INN);
1-Hydroxypioglitazone |
|---|
| Formula |
C19H20N2O4S
|
|---|
| Exact mass |
372.1144
|
|---|
| Mol weight |
372.44
|
|---|
| Structure |
|
|---|
| Class |
|
|---|
| Remark |
|
|---|
| Efficacy |
Peroxisome proliferator-activated receptor (PPAR) gamma agonist |
|---|
| Comment |
Treatment of X-linked adrenoleukodystrophy
|
|---|
| Target |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16AX Various alimentary tract and metabolism products
A16AX23 Leriglitazone
D11603 Leriglitazone (USAN/INN)
Drug groups [BR:br08330]
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
DG01683 Thiazolidinedione
DG03060 Leriglitazone
D11603 Leriglitazone
DG02044 Hypoglycemic agent
DG01683 Thiazolidinedione
DG03060 Leriglitazone
D11603 Leriglitazone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
NR1C3 (PPARG)
D11603 Leriglitazone (USAN/INN)
Drug groups [BR:br08330]
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
DG01683 Thiazolidinedione
DG03060 Leriglitazone
DG02044 Hypoglycemic agent
DG01683 Thiazolidinedione
DG03060 Leriglitazone
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 26
1 C1y C 24.1232 -15.3821
2 C1b C 22.9346 -14.6829
3 C5x C 24.1232 -16.7805
4 S2x S 25.4517 -14.9626
5 C8y C 21.7460 -15.3821
6 N1x N 25.4517 -17.2000
7 O5x O 23.0045 -17.6195
8 C5x C 26.2907 -16.0813
9 C8x C 20.4875 -14.6829
10 C8x C 21.7460 -16.7805
11 O5x O 27.6891 -16.0813
12 C8x C 19.2989 -15.3821
13 C8x C 20.4875 -17.4797
14 C8y C 19.2989 -16.7805
15 O2a O 18.1102 -17.4797
16 C1b C 16.8517 -16.7805
17 C1b C 15.6631 -17.4797
18 C8y C 14.4745 -16.7805
19 C8x C 14.4745 -15.3821
20 N5x N 13.2159 -17.4797
21 C8x C 13.2159 -14.6829
22 C8x C 12.0273 -16.7805
23 C8y C 12.0273 -15.3821
24 C1c C 10.8387 -14.6829
25 C1a C 9.5802 -15.3821
26 O1a O 10.8559 -13.3000
BOND 28
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 1
6 3 7 2
7 4 8 1
8 5 9 2
9 5 10 1
10 8 11 2
11 9 12 1
12 10 13 2
13 12 14 2
14 14 15 1
15 15 16 1
16 16 17 1
17 17 18 1
18 18 19 2
19 18 20 1
20 19 21 1
21 20 22 2
22 21 23 2
23 23 24 1
24 24 25 1
25 6 8 1
26 13 14 1
27 22 23 1
28 24 26 1
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