| Entry |
|
|---|
| Name |
Volanesorsen (USAN/INN);
Waylivra (TN) |
|---|
| Formula |
C230H320N63O125P19S19
|
|---|
| Exact mass |
7160.0328
|
|---|
| Mol weight |
7165.13
|
|---|
| Sequence |
DNA, d(P-thio) ([2′-O-(2-methoxyethyl) ]rA-[2′-O-(2-methoxyethyl)
]rG-[2′-O-(2-methoxyethyl) ]m5rC-[2′-O-(2-methoxyethyl)
]m5rU-[2′-O-(2-methoxyethyl)
]m5rU-m5C-T-T-G-T-m5C-m5C-A-G-m5C-[2′-O-(2-methoxyethyl)
]m5rU-[2′-O-(2-methoxyethyl) ]m5rU-[2′-O-(2-methoxyethyl)
]m5rU-[2′-O-(2-methoxyethyl) ]rA-[2′-O-(2-methoxyethyl) ]m5rU) |
|---|
| Type |
Nucleotide |
|---|
| Remark |
|
|---|
| Efficacy |
Antihyperlipidemic, Apolipoprotein C3 inhibitor |
|---|
| Type |
Antisense oligonucleotide |
|---|
| Comment |
Treatment of familial chylomicronemia syndrome
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C10 LIPID MODIFYING AGENTS
C10A LIPID MODIFYING AGENTS, PLAIN
C10AX Other lipid modifying agents
C10AX18 Volanesorsen
D11648 Volanesorsen (USAN/INN)
Target-based classification of drugs [BR:br08310]
Not elsewhere classified
Organismal systems
Digestive system
APOC3
D11648 Volanesorsen (USAN/INN)
|
|---|
| Other DBs |
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|---|
| LinkDB |
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|---|
