KEGG   DRUG: Volanesorsen sodium
Entry
D11650                      Drug                                   
Name
Volanesorsen sodium (USAN);
Waylivra (TN)
Formula
C230H320N63O125P19S19. 19Na
Exact mass
7596.8384
Mol weight
7601.891
Remark
ATC code: C10AX18
Chemical structure group: DG03070
Efficacy
Antihyperlipidemic, Apolipoprotein C3 inhibitor
Comment
Antisense oligonucleotide
Treatment of familial chylomicronemia syndrome
Target
APOC3 [HSA:345] [KO:K08759]
  Pathway
hsa03320  PPAR signaling pathway
hsa04979  Cholesterol metabolism
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C10 LIPID MODIFYING AGENTS
   C10A LIPID MODIFYING AGENTS, PLAIN
    C10AX Other lipid modifying agents
     C10AX18 Volanesorsen
      D11650  Volanesorsen sodium (USAN)
Target-based classification of drugs [BR:br08310]
 Not elsewhere classified
  Organismal systems
   Digestive system
    APOC3
     D11650  Volanesorsen sodium (USAN)
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D11650
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11650
Other DBs
CAS: 1573402-50-2
PubChem: 405226517
LinkDB

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