| Entry |
|
|---|
| Name |
Fosmanogepix (USAN/INN) |
|---|
| Formula |
C22H21N4O6P
|
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| Exact mass |
468.1199
|
|---|
| Mol weight |
468.40
|
|---|
| Structure |
|
|---|
| Efficacy |
Antifungal, Protein biosynthesis inhibitor |
|---|
| Comment |
Treatment of invasive fungal infections
|
|---|
| Target |
|
|---|
| Pathway |
| ko00563 | Glycosylphosphatidylinositol (GPI)-anchor biosynthesis |
|
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| Other DBs |
|
|---|
| LinkDB |
|
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| KCF data |
ATOM 33
1 N5y N 8.4700 -17.9900 #+
2 C8x C 8.4700 -19.3900
3 C8x C 9.6600 -20.0900
4 C8x C 10.9200 -19.3900
5 C8y C 10.9200 -17.9900
6 C8y C 9.6600 -17.2900
7 C1b C 7.2800 -17.2900
8 O2b O 6.0900 -17.9900
9 N1a N 9.6600 -15.8900
10 C8y C 12.1100 -17.2900
11 C8x C 13.2300 -18.1300
12 C8y C 14.3500 -17.2900
13 N5x N 13.9300 -15.9600
14 O2x O 12.5300 -15.9600
15 C1b C 15.5400 -17.9900
16 C8y C 16.7300 -17.2900
17 C8x C 17.9200 -17.9900
18 C8x C 19.1800 -17.2900
19 C8y C 19.1800 -15.8900
20 C8x C 17.9900 -15.1900
21 C8x C 16.7300 -15.8900
22 C1b C 20.3953 -15.1949
23 O2a O 21.5837 -15.8877
24 C8y C 22.8501 -15.2035
25 C8x C 23.9613 -15.8919
26 C8x C 25.1766 -15.1969
27 C8x C 25.1824 -13.7969
28 C8x C 24.0012 -13.1085
29 N5x N 22.7859 -13.8035
30 P1b P 4.8719 -17.2999
31 O1c O 3.6595 -16.5999
32 O1c O 5.5719 -16.0874 #-
33 O1c O 4.1719 -18.5123
BOND 36
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 7 8 1
9 6 9 1
10 5 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 13 14 1
15 10 14 1
16 12 15 1
17 15 16 1
18 16 17 2
19 17 18 1
20 18 19 2
21 19 20 1
22 20 21 2
23 16 21 1
24 19 22 1
25 22 23 1
26 23 24 1
27 24 25 2
28 25 26 1
29 26 27 2
30 27 28 1
31 28 29 2
32 24 29 1
33 8 30 1
34 30 31 2
35 30 32 1
36 30 33 1
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