| Entry |
|
|---|
| Name |
Lazucirnon (USAN) |
|---|
| Formula |
C27H34ClN5O3
|
|---|
| Exact mass |
511.2350
|
|---|
| Mol weight |
512.04
|
|---|
| Structure |
|
|---|
| Remark |
|
|---|
| Efficacy |
Immunomodulator |
|---|
| Comment |
Treatment of wet age-related macular degeneration, Parkinson's disease, Alzheimer's disease and/or eosinophilic disease
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04060 | Cytokine-cytokine receptor interaction |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Cytokines and receptors
Cytokines
Chemokines
CCL11
D11741 Lazucirnon (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 36
1 N1y N 14.9104 -16.1004
2 C1x C 14.9104 -17.5004
3 C1x C 16.1704 -18.2004
4 C1y C 17.3604 -17.5004
5 C1x C 17.3604 -16.1004
6 C1x C 16.1704 -15.4003
7 N1y N 18.5505 -18.2004
8 C5x C 18.1305 -19.5305
9 C1x C 19.2505 -20.3705
10 C1x C 20.3705 -19.5305
11 C1y C 19.9505 -18.2004
12 O5x O 16.8004 -19.9505
13 C5a C 21.1406 -17.5004
14 N1b N 22.3306 -18.2004
15 C8y C 23.5487 -17.5103
16 O5a O 21.1406 -16.1004
17 N5x N 24.7302 -18.2054
18 C8y C 25.9484 -17.5154
19 C8x C 25.9599 -16.1154
20 C8y C 24.7784 -15.4202
21 C8x C 23.4902 -16.1103
22 C1a C 27.1649 -18.2313
23 C5a C 24.8068 -14.0005
24 N1c N 26.0129 -13.3358
25 O5a O 23.5894 -13.2648
26 C1a C 27.2471 -14.0808
27 C1a C 26.0405 -11.9702
28 C1b C 13.7033 -15.3901
29 C8y C 12.4937 -16.0754
30 C8x C 11.2734 -15.3570
31 C8x C 10.0551 -16.0467
32 C8y C 10.1132 -17.4467
33 C8y C 11.2635 -18.1650
34 C8x C 12.4818 -17.4754
35 X Cl 8.8861 -18.1612
36 C1a C 11.3024 -19.5995
BOND 39
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 7 11 1
13 8 12 2
14 13 14 1
15 11 13 1 #Up
16 14 15 1
17 13 16 2
18 15 17 2
19 17 18 1
20 18 19 2
21 19 20 1
22 20 21 2
23 15 21 1
24 18 22 1
25 20 23 1
26 23 24 1
27 23 25 2
28 24 26 1
29 24 27 1
30 1 28 1
31 28 29 1
32 29 30 2
33 30 31 1
34 31 32 2
35 32 33 1
36 33 34 2
37 29 34 1
38 32 35 1
39 33 36 1
|
|---|
