KEGG   DRUG: Avacincaptad pegol sodium
Entry
D11748                      Drug                                   
Name
Avacincaptad pegol sodium (JAN/USAN);
Izervay (TN)
Product
IZERVAY (Astellas Pharma US)
Formula
C395H453F21N142Na39O262P39. (C2H4O)2n
Sequence
cgccgcgguc ucaggcgcug agucugaguu uaccugcgt
  Type
Nucleotide
Remark
Therapeutic category: 1319
ATC code: S01XA32
Product: D11748<JP/US>
Efficacy
Aging-related macular degeneration therapeutic agent
  Disease
Age-related macular degeneration, geographic atrophy [DS:H00821]
  Type
RNA aptamer
Comment
Treatment of dry-AMD and wet-AMD
Target
C5 [HSA:727] [KO:K03994]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04610  Complement and coagulation cascades
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01X OTHER OPHTHALMOLOGICALS
    S01XA Other ophthalmologicals
     S01XA32 Avacincaptad pegol
      D11748  Avacincaptad pegol sodium (JAN/USAN) <US>
USP drug classification [BR:br08302]
 Ophthalmic Agents
  Ophthalmic Agents, Other
   Avacincaptad Pegol
    D11748  Avacincaptad pegol sodium (JAN/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1319  Others
     D11748  Avacincaptad pegol sodium (JAN/USAN)
Target-based classification of drugs [BR:br08310]
 Peptidases and inhibitors
  Peptidase inhibitors
   alpha2M family
    C5
     D11748  Avacincaptad pegol sodium (JAN/USAN) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D11748
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D11748
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11748
Other DBs
CAS: 1491144-00-3
PubChem: 405226614
LinkDB

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