| Entry |
|
| Name |
Mivavotinib (USAN/INN) |
| Formula |
C17H21FN6O
|
| Exact mass |
344.1761
|
| Mol weight |
344.39
|
| Structure |

|
| Remark |
|
| Efficacy |
Antineoplastic, Tyrosin kinase inhibitor |
| Comment |
Treatment of hematological and solid malignancies
|
| Target |
|
| Pathway |
| hsa04662 | B cell receptor signaling pathway |
|
| Brite |
Target-based classification of drugs [BR:br08310]
Protein kinases
Non-receptor tyrosine kinases
SYK family
SYK
D11789 Mivavotinib (USAN/INN)
|
| Other DBs |
|
| LinkDB |
|
| KCF data |
ATOM 25
1 C8y C 13.8600 -14.3500
2 C8y C 13.8600 -15.7500
3 N5x N 15.0724 -16.4500
4 C8y C 16.2849 -15.7500
5 C8y C 16.2849 -14.3500
6 C8y C 15.0724 -13.6500
7 C5x C 17.3253 -13.4132
8 N1x N 16.7559 -12.1342
9 C1x C 15.3635 -12.2806
10 O5x O 18.7333 -13.7119
11 X F 12.6476 -13.6500
12 N1b N 12.6476 -16.4500
13 C1y C 11.4521 -15.7596
14 C1x C 11.4520 -14.3503
15 C1x C 10.2396 -13.6503
16 C1x C 9.0272 -14.3503
17 C1x C 9.0272 -15.7597
18 C1y C 10.2396 -16.4596
19 C8y C 17.5149 -16.4624
20 C8x C 17.5349 -17.8496
21 N5x N 18.8603 -18.2592
22 N4y N 19.6595 -17.1253
23 C8x C 18.8280 -16.0148
24 C1a C 21.0864 -17.1745
25 N1a N 10.2395 -17.8499
BOND 28
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 6 9 1
11 7 10 2
12 1 11 1
13 2 12 1
14 13 12 1 #Up
15 13 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 13 18 1
21 4 19 1
22 19 20 1
23 20 21 2
24 21 22 1
25 22 23 1
26 19 23 2
27 22 24 1
28 18 25 1 #Up
|