KEGG   DRUG: Brexucabtagene autoleucel
Entry
D11880                      Drug                                   
Name
Brexucabtagene autoleucel (USAN);
Tecartus (TN)
Product
Remark
ATC code: L01XL06
Product: D11880<US>
Efficacy
Antineoplastic, Anti-CD19 CAR-T cell
  Disease
Mantle cell lymphoma [DS:H01464]
Comment
Cellular therapy product
Target
CD19 [HSA:930] [KO:K06465]
  Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04640  Hematopoietic cell lineage
hsa04662  B cell receptor signaling pathway
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XL Antineoplastic cell and gene therapy
     L01XL06 Brexucabtagene autoleucel
      D11880  Brexucabtagene autoleucel (USAN) <US>
Target-based classification of drugs [BR:br08310]
 Cell surface molecules and ligands
  Other cell surface molecules
   CD molecules
    CD19
     D11880  Brexucabtagene autoleucel (USAN) <US>
New drug approvals in the USA [br08319.html]
 Cellular and gene therapy products
  D11880
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D11880
 Cellular and gene therapy products
  D11880
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11880
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