| Entry |
|
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| Name |
Danuglipron (USAN) |
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| Formula |
C31H30FN5O4
|
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| Exact mass |
555.2282
|
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| Mol weight |
555.60
|
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| Structure |
|
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| Class |
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01493 GLP-1 receptor agonist
|
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| Remark |
|
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| Efficacy |
Antidiabetic, Glucagon-like peptide 1 (GLP-1) receptor agonist |
|---|
| Comment |
Treatment of type 2 diabetes mellitus, obesity and non-alcoholic steatohepatitis (NASH)
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
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| Brite |
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01493 GLP-1 receptor agonist
DG03125 Danuglipron
D11910 Danuglipron
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Secretin receptor family
Glucagon
GLP1R
D11910 Danuglipron (USAN)
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01493 GLP-1 receptor agonist
DG03125 Danuglipron
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 41
1 C8y C 11.1300 -13.5100
2 C8x C 11.1300 -14.9100
3 C8y C 12.3424 -15.6100
4 C8y C 13.5549 -14.9100
5 C8x C 13.5549 -13.5100
6 C8x C 12.3424 -12.8100
7 C3b C 9.9176 -12.8100
8 N3a N 8.7051 -12.1100
9 X F 12.3424 -17.0098
10 C1b C 14.7860 -15.6210
11 O2a O 15.9912 -14.9253
12 C8y C 17.1735 -15.6081
13 C8x C 17.1734 -17.0098
14 C8x C 18.3858 -17.7099
15 C8x C 19.5983 -17.0100
16 C8y C 19.5984 -15.6083
17 N5x N 18.3860 -14.9082
18 C1y C 20.8114 -14.9082
19 C1x C 22.0084 -15.5996
20 C1x C 23.2210 -14.8998
21 N1y N 23.2212 -13.4998
22 C1x C 22.0242 -12.8084
23 C1x C 20.8116 -13.5082
24 C1b C 24.4433 -12.7944
25 C8y C 25.6523 -13.4926
26 N4y N 25.5988 -14.9098
27 C8y C 26.9248 -15.3993
28 C8y C 27.8001 -14.2893
29 N5x N 27.0149 -13.1140
30 C1b C 24.4500 -15.6788
31 C1y C 24.4500 -17.0788
32 O2x O 23.4496 -18.0794
33 C1x C 24.4502 -19.0798
34 C1x C 25.4506 -18.0792
35 C8x C 27.4434 -16.6997
36 C8y C 28.8289 -16.9008
37 C8x C 29.7041 -15.7908
38 C8x C 29.1856 -14.4904
39 C6a C 29.3387 -18.1782
40 O6a O 30.7186 -18.3781
41 O6a O 28.4581 -19.2953
BOND 46
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 7 8 3
9 3 9 1
10 4 10 1
11 10 11 1
12 11 12 1
13 12 13 2
14 13 14 1
15 14 15 2
16 15 16 1
17 16 17 2
18 12 17 1
19 16 18 1
20 18 19 1
21 19 20 1
22 20 21 1
23 21 22 1
24 22 23 1
25 18 23 1
26 21 24 1
27 24 25 1
28 25 26 1
29 26 27 1
30 27 28 2
31 28 29 1
32 25 29 2
33 26 30 1
34 31 30 1 #Down
35 31 32 1
36 32 33 1
37 33 34 1
38 31 34 1
39 27 35 1
40 35 36 2
41 36 37 1
42 37 38 2
43 28 38 1
44 36 39 1
45 39 40 1
46 39 41 2
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