KEGG   DRUG: Odesivimab
Entry
D11921                      Drug                                   
Name
Odesivimab (USAN);
Odesivimab-ebgn
Formula
C6506H10024N1720O2030S42
Exact mass
146072.2291
Mol weight
146162.2408
Sequence
(Heavy chain)
EVQLVESGGG LVQPGGSLRL SCAASGFTFS SYDMHWVRQA TGKGLEWVSA IGTAGDTYYP
GSVKGRFTIS RENAKNSLYL QMNSLRAGDT AVYYCARTWF GELYFDYWGQ GTLVTVSSAS
TKGPSVFPLA PSSKSTSGGT AALGCLVKDY FPEPVTVSWN SGALTSGVHT FPAVLQSSGL
YSLSSVVTVP SSSLGTQTYI CNVNHKPSNT KVDKKVEPKS CDKTHTCPPC PAPELLGGPS
VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST
YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY LPPSRDELT
KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ
GNVFSCSVMH EALHNHYTQK SLSLSPGK
(Light chain)
DIVMTQSPDS LAVSLGERAT INCKSSQSVL YSSNNKNYLA WYQQKPGQPP KLLIYWASTR
ESGVPDRFSG SGSGTEFTLT ITSLQAEDVA VYYCQQYYSS PLTFGGGTKV EIKRTVAAPS
VFIFPPSDEQ LKSGTASVVC LLNNFYPREA KVQWKVDNAL QSGNSQESVT EQDSKDSTYS
LSSTLTLSKA DYEKHKVYAC EVTHQGLSSP VTKSFNRGEC
(Disulfide bridge: H22-H95, H145-H201, H221-L220, H227-H'227, H230-H'230, H262-H322, H368-H426, H'22-H'95, H'145-H'201, H'221-L'220, H'262-H'322, H'368-H'426, L23-L94, L140-L200, L'23-L'94, L'140-L'200)
  Type
Peptide
Remark
Product (mixture): D11922<US>
Efficacy
Antiviral
Comment
Monoclonal antibody
Treatment of Ebola virus disease
Target
Zaire ebolavirus glycoprotein [KO:K24534]
  Pathway
ko03230  Viral genome structure
Brite
Antimicrobials [BR:br08307]
 Antivirals
  Entry, fusion or uncoating inhibitor
   Ebolavirus glycoprotein
    D11921  Odesivimab (USAN)
Other DBs
CAS: 2135632-30-1
LinkDB

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