KEGG   DRUG: Lumasiran
Entry
D11925                      Drug                                   
Name
Lumasiran (USAN/INN)
Formula
C530H712F10N173O320P43S6
Exact mass
16332.1641
Mol weight
16340.55
Remark
ATC code: A16AX18
Chemical structure group: DG03131
Product (DG03131): D11926<US>
Efficacy
Oxalate production reduction
  Type
RNA interference (RNAi) drug
Comment
Treatment of primary hyperoxaluria type 1
Target
HAO1 [HSA:54363] [KO:K11517] (mRNA)
  Pathway
hsa00630  Glyoxylate and dicarboxylate metabolism
hsa04146  Peroxisome
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
   A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
    A16AX Various alimentary tract and metabolism products
     A16AX18 Lumasiran
      D11925  Lumasiran (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Oxidases
    HAO1
     D11925  Lumasiran (USAN/INN)
Other DBs
CAS: 1834610-13-7
PubChem: 497620338
LinkDB

» Japanese version   » Back

DBGET integrated database retrieval system