KEGG   DRUG: Casimersen
Entry
D11988                      Drug                                   

Name
Casimersen (USAN/INN);
Amondys 45 (TN)
Product
Formula
C268H424N124O95P22
Exact mass
7580.6386
Mol weight
7584.4307
Remark
Product: D11988<US>
Efficacy
Translation inhibitor
  Disease
Duchenne muscular dystrophy (DMD variant amenable to exon 45 skipping) [DS:H01963]
Comment
Antisense oligonucleotide
Treatment of Duchenne muscular dystrophy
Target
DMD* [HSA_VAR:1756v1] [HSA:1756] [KO:K10366] (pre-mRNA exon45)
Brite
Target-based classification of drugs [BR:br08310]
 Not elsewhere classified
  Cellular process
   Cytoskeleton
    DMD* [HSA_VAR:1756v1]
     D11988  Casimersen (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D11988
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11988
Other DBs
CAS: 1422958-19-7
LinkDB

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