KEGG   DRUG: Pacanalotamab
Entry
D12010                      Drug                                   
Name
Pacanalotamab (USAN)
Formula
C2373H3584N654O747S14
Exact mass
53641.8655
Mol weight
53674.6917
Sequence
QVQLVQSGAE VKKPGASVKV SCKASGYTFT NHIIHWVRQA PGQGLEWMGY INPYPGYHAY
NEKFQGRATM TSDTSTSTVY MELSSLRSED TAVYYCARDG YYRDTDVLDY WGQGTLVTVS
SGGGGSGGGG SGGGGSDIQM TQSPSSLSAS VGDRVTITCQ ASQDISNYLN WYQQKPGKAP
KLLIYYTSRL HTGVPSRFSG SGSGTDFTFT ISSLEPEDIA TYYCQQGNTL PWTFGQGTKV
EIKSGGGGSE VQLVESGGGL VQPGGSLKLS CAASGFTFNK YAMNWVRQAP GKGLEWVARI
RSKYNNYATY YADSVKDRFT ISRDDSKNTA YLQMNNLKTE DTAVYYCVRH GNFGNSYISY
WAYWGQGTLV TVSSGGGGSG GGGSGGGGSQ TVVTQEPSLT VSPGGTVTLT CGSSTGAVTS
GNYPNWVQQK PGQAPRGLIG GTKFLAPGTP ARFSGSLLGG KAALTLSGVQ PEDEAEYYCV
LWYSNRWVFG GGTKLTVLHH HHHH
(Disulfide bridge: 22-96, 159-224, 271-347, 411-479)
  Type
Peptide
Efficacy
Antineoplastic
Comment
Monoclonal antibody
Treatment of multiple myeloma
Target
TNFRSF17 (BCMA, CD269) [HSA:608] [KO:K05153]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04672  Intestinal immune network for IgA production
Brite
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   Tumor necrosis factor receptors
    TNFRSF17 (BCMA, CD269)
     D12010  Pacanalotamab (USAN)
Other DBs
CAS: 2251756-52-0
LinkDB

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