KEGG   DRUG: Lilotomab
Entry
D12124                      Drug                                   
Name
Lilotomab (USAN/INN)
Formula
C6442H9862N1696O2028S54
Exact mass
145156.5627
Mol weight
145246.8901
Sequence
(Heavy chain)
EIQLQQSGPE LVKPGASVKV SCKASGYSFT DYNMYWVKQS HGKSLEWIGY IDPYNGDTTY
NQKFKGKATL TVDKSSSTAF IHLNSLTSED SAVYYCARSP YGHYAMDYWG QGTSVTVSSA
KTTPPSVYPL APGSAAQTNS MVTLGCLVKG YFPEPVTVTW NSGSLSSGVH TFPAVLQSDL
YTLSSSVTVP SSTWPSETVT CNVAHPASST KVDKKIVPRD CGCKPCICTV PEVSSVFIFP
PKPKDVLTIT LTPKVTCVVV DISKDDPEVQ FSWFVDDVEV HTAQTQPREE QFNSTFRSVS
ELPIMHQDWL NGKEFKCRVN SAAFPAPIEK TISKTKGRPK APQVYTIPPP KEQMAKDKVS
LTCMITDFFP EDITVEWQWN GQPAENYKNT QPIMDTDGSY FVYSKLNVQK SNWEAGNTFT
CSVLHEGLHN HHTEKSLSHS PGK
(Light chain)
DIVMTQSHKL LSTSVGDRVS ITCKASQDVS TAVDWYQQKP GQSPKLLINW ASTRHTGVPD
RFTGSGSGTD YTLTISSMQA EDLALYYCRQ HYSTPFTFGS GTKLEIKRAD AAPTVSIFPP
SSEQLTSGGA SVVCFLNNFY PKDINVKWKI DGSERQNGVL NSWTDQDSKD STYSMSSTLT
LTKDEYERHN SYTCEATHKT STSPIVKSFN RNEC
(Disulfide bridge: H22-H96, H146-H201, H221-L214, H223-H'223, H226-H'226, H228-H'228, H257-H317, H363-H421, H'22-H'96, H'146-H'201, H'221-L'214, H'257-H'317, H'363-H'421, L23-L88, L134-L194, L'23-L'88, L'134-L'194)
  Type
Peptide
Efficacy
Antineoplastic
Comment
Monoclonal antibody
Target
CD37 [HSA:951] [KO:K06475]
  Pathway
hsa04640  Hematopoietic cell lineage
Brite
Target-based classification of drugs [BR:br08310]
 Cell surface molecules and ligands
  Other cell surface molecules
   CD molecules
    CD37
     D12124  Lilotomab (USAN/INN)
Other DBs
CAS: 1453362-55-4
LinkDB

» Japanese version   » Back

DBGET integrated database retrieval system