KEGG   DRUG: Emerfetamab
Entry
D12141                      Drug                                   

Name
Emerfetamab (USAN)
Formula
C4707H7205N1271O1483S39
Exact mass
106510.6556
Mol weight
106576.7335
Sequence
QVQLVQSGAE VKKPGESVKV SCKASGYTFT NYGMNWVKQA PGQCLEWMGW INTYTGEPTY
ADKFQGRVTM TTDTSTSTAY MEIRNLGGDD TAVYYCARWS WSDGYYVYFD YWGQGTSVTV
SSGGGGSGGG GSGGGGSDIV MTQSPDSLTV SLGERTTINC KSSQSVLDSS TNKNSLAWYQ
QKPGQPPKLL LSWASTRESG IPDRFSGSGS GTDFTLTIDS PQPEDSATYY CQQSAHFPIT
FGCGTRLEIK SGGGGSEVQL VESGGGLVQP GGSLKLSCAA SGFTFNKYAM NWVRQAPGKG
LEWVARIRSK YNNYATYYAD SVKDRFTISR DDSKNTAYLQ MNNLKTEDTA VYYCVRHGNF
GNSYISYWAY WGQGTLVTVS SGGGGSGGGG SGGGGSQTVV TQEPSLTVSP GGTVTLTCGS
STGAVTSGNY PNWVQQKPGQ APRGLIGGTK FLAPGTPARF SGSLLGGKAA LTLSGVQPED
EAEYYCVLWY SNRWVFGGGT KLTVLGGGGD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL
MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP CEEQYGSTYR CVSVLTVLHQ
DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSREEMTKN QVSLTCLVKG
FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA
LHNHYTQKSL SLSPGKGGGG SGGGGSGGGG SGGGGSGGGG SGGGGSDKTH TCPPCPAPEL
LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPCEE
QYGSTYRCVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS
REEMTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK
SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGK
(Disulfide bridge: 22-96, 44-243, 160-231, 278-354, 418-486, 515-772, 518-775, 550-610, 581-591, 656-714, 807-867, 838-848, 913-971)
  Type
Peptide
Efficacy
Antineoplastic, Anti-CD33 antibody
Comment
Monoclonal antibody
Treatment of patients with acute myeloid leukemia
Target
CD33 [HSA:945] [KO:K06473]
  Pathway
hsa04640  Hematopoietic cell lineage
Brite
Target-based classification of drugs [BR:br08310]
 Cell surface molecules and ligands
  Cell adhesion molecules: Ig superfamiy
   SIGLEC family
    CD33
     D12141  Emerfetamab (USAN)
Other DBs
CAS: 2250261-27-7
LinkDB

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