KEGG   DRUG: Mazdutide
Entry
D12225                      Drug                                   
Name
Mazdutide (USAN/INN)
Formula
C210H322N46O67
Exact mass
4560.3203
Mol weight
4563.07
Structure
Sequence
HXQGTFTSDY SKYLDEKKAK EFVEWLLEGG PSSG
  Type
Peptide
Class
Antidiabetic agent
 DG02044  Hypoglycemic agent
  DG01493  GLP-1 receptor agonist
 DG03355  Oxyntomodulin analog
Efficacy
Antidiabetic, Antiobesity, Glucagon-like peptide 1 (GLP-1) receptor agonist, Glucagon receptor agonist
  Type
Modified peptide
Comment
Treatment of diabetes, NASH and obesity
Target
GLP1R [HSA:2740] [KO:K04581]
GCGR [HSA:2642] [KO:K04583]
  Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04911  Insulin secretion
hsa04922  Glucagon signaling pathway
Interaction
Brite
Drug groups [BR:br08330]
 Antidiabetic agent
  DG02044  Hypoglycemic agent
   DG01493  GLP-1 receptor agonist
    D12225  Mazdutide
  DG03355  Oxyntomodulin analog
   D12225  Mazdutide
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Glucagon
    GLP1R
     D12225  Mazdutide (USAN/INN)
    GCGR
     D12225  Mazdutide (USAN/INN)
Other DBs
CAS: 2259884-03-0
PubChem: 497620638
LinkDB

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