| Entry |
|
|---|
| Name |
Onternabez (USAN) |
|---|
| Formula |
C27H42O3
|
|---|
| Exact mass |
414.3134
|
|---|
| Mol weight |
414.62
|
|---|
| Structure |
|
|---|
| Efficacy |
Respiratory response inducer, Cannabinoid receptor agonist |
|---|
| Comment |
For the treatment of acute respiratory distress syndrome (ARDS) associated with SARS-CoV-2 (COVID-19) infection
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Cannabinoid
CNR
D12305 Onternabez (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 30
1 C1z C 6.7900 -13.8600
2 C1y C 6.7900 -12.4600
3 C2y C 7.9800 -11.7600
4 C2x C 9.2400 -12.4600
5 C1y C 9.2400 -13.8600
6 C1y C 7.9800 -14.5600
7 C8y C 10.4300 -14.5600
8 C8y C 11.6200 -13.8600
9 C8x C 12.8800 -14.5600
10 C8y C 12.8800 -15.9600
11 C8x C 11.6900 -16.6600
12 C8y C 10.4300 -15.9600
13 O2a O 9.2400 -16.6600
14 C1a C 8.0500 -15.9600
15 O2a O 11.6200 -12.4600
16 C1a C 12.8100 -11.7600
17 C1b C 7.9800 -10.3600
18 O1a O 6.7900 -9.6600
19 C1a C 6.0900 -15.0500
20 C1a C 5.4600 -13.5100
21 C1x C 7.9800 -13.1600
22 C1d C 14.0700 -16.6600
23 C1b C 15.2600 -15.9600
24 C1b C 16.4500 -16.6600
25 C1b C 17.6400 -15.9600
26 C1b C 18.8300 -16.6600
27 C1b C 20.0200 -15.9600
28 C1a C 21.2100 -16.6600
29 C1a C 13.3700 -17.9200
30 C1a C 14.7700 -17.9200
BOND 32
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 5 7 1 #Down
8 7 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 11 12 2
13 7 12 1
14 12 13 1
15 13 14 1
16 8 15 1
17 15 16 1
18 3 17 1
19 17 18 1
20 1 19 1
21 1 20 1
22 6 21 1 #Down
23 2 21 1 #Down
24 10 22 1
25 22 23 1
26 23 24 1
27 24 25 1
28 25 26 1
29 26 27 1
30 27 28 1
31 22 29 1
32 22 30 1
|
|---|
