KEGG   DRUG: Onternabez
Entry
D12305                      Drug                                   
Name
Onternabez (USAN)
Formula
C27H42O3
Exact mass
414.3134
Mol weight
414.6206
Structure
Efficacy
Respiratory response inducer, Cannabinoid receptor agonist
Comment
For the treatment of acute respiratory distress syndrome (ARDS) associated with SARS-CoV-2 (COVID-19) infection
Target
CNR [HSA:1268 1269] [KO:K04277 K04278]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Cannabinoid
    CNR
     D12305  Onternabez (USAN)
Other DBs
CAS: 256934-39-1
LinkDB
KCF data

ATOM        30
            1   C1z C     6.7900  -13.8600
            2   C1y C     6.7900  -12.4600
            3   C2y C     7.9800  -11.7600
            4   C2x C     9.2400  -12.4600
            5   C1y C     9.2400  -13.8600
            6   C1y C     7.9800  -14.5600
            7   C8y C    10.4300  -14.5600
            8   C8y C    11.6200  -13.8600
            9   C8x C    12.8800  -14.5600
            10  C8y C    12.8800  -15.9600
            11  C8x C    11.6900  -16.6600
            12  C8y C    10.4300  -15.9600
            13  O2a O     9.2400  -16.6600
            14  C1a C     8.0500  -15.9600
            15  O2a O    11.6200  -12.4600
            16  C1a C    12.8100  -11.7600
            17  C1b C     7.9800  -10.3600
            18  O1a O     6.7900   -9.6600
            19  C1a C     6.0900  -15.0500
            20  C1a C     5.4600  -13.5100
            21  C1x C     7.9800  -13.1600
            22  C1d C    14.0700  -16.6600
            23  C1b C    15.2600  -15.9600
            24  C1b C    16.4500  -16.6600
            25  C1b C    17.6400  -15.9600
            26  C1b C    18.8300  -16.6600
            27  C1b C    20.0200  -15.9600
            28  C1a C    21.2100  -16.6600
            29  C1a C    13.3700  -17.9200
            30  C1a C    14.7700  -17.9200
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 1 #Down
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12   11  12 2
            13    7  12 1
            14   12  13 1
            15   13  14 1
            16    8  15 1
            17   15  16 1
            18    3  17 1
            19   17  18 1
            20    1  19 1
            21    1  20 1
            22    6  21 1 #Down
            23    2  21 1 #Down
            24   10  22 1
            25   22  23 1
            26   23  24 1
            27   24  25 1
            28   25  26 1
            29   26  27 1
            30   27  28 1
            31   22  29 1
            32   22  30 1

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