| Entry |
|
|---|
| Name |
Bortezomib hydrate (JAN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C19H25BN4O4. H2O
|
|---|
| Exact mass |
402.2075
|
|---|
| Mol weight |
402.25
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG03134 Proteasome inhibitor
|
|---|
| Remark |
| Therapeutic category: | 4291 |
| Product (DG03219): | D03150<JP/US> D12311<JP/US> |
|
|---|
| Efficacy |
Antineoplastic, Proteasome inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01X OTHER ANTINEOPLASTIC AGENTS
L01XG Proteasome inhibitors
L01XG01 Bortezomib
D12311 Bortezomib hydrate (JAN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
42 Antineoplastics
429 Miscellaneous
4291 Other Antitumors
D12311 Bortezomib hydrate (JAN)
Drug groups [BR:br08330]
Antineoplastic
DG03134 Proteasome inhibitor
DG03219 Bortezomib
D12311 Bortezomib hydrate
Target-based classification of drugs [BR:br08310]
Peptidases and inhibitors
Threonine peptidases
Proteasome family
PSMB5
D12311 Bortezomib hydrate (JAN) <JP/US>
Drug groups [BR:br08330]
Antineoplastic
DG03134 Proteasome inhibitor
DG03219 Bortezomib
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 29
1 N1b N 16.8849 -17.2360
2 C1c C 18.0776 -16.6046
3 C8x C 12.0440 -17.2360
4 C8x C 12.0440 -18.6392
5 N5x N 13.2367 -19.3408
6 C8x C 14.4995 -18.6392
7 C8y C 14.4995 -17.2360
8 N5x N 13.2367 -16.6046
9 C5a C 15.6922 -16.6046
10 O5a O 15.6922 -15.2014
11 C5a C 19.2703 -17.3062
12 N1b N 20.4630 -16.6046
13 C1c C 21.6557 -17.3062
14 C1b C 22.8484 -16.6046
15 C1c C 24.0411 -17.3062
16 C1a C 25.2338 -16.6046
17 C1a C 24.0411 -18.6392
18 O5a O 19.2703 -18.6392
19 C1b C 18.0776 -15.2014
20 C8y C 19.3405 -14.4999
21 C8x C 20.4630 -15.2014
22 C8x C 21.7259 -14.4999
23 C8x C 21.7259 -13.0967
24 C8x C 20.5332 -12.4652
25 C8x C 19.3405 -13.0967
26 Z B 21.6557 -19.2005
27 O1a O 20.4630 -19.9021
28 O1a O 22.8484 -19.9021
29 O0 O 28.4200 -18.6900
BOND 29
1 3 4 2
2 4 5 1
3 5 6 2
4 6 7 1
5 7 8 2
6 8 3 1
7 7 9 1
8 9 1 1
9 2 1 1
10 9 10 2
11 2 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 15 17 1
18 11 18 2
19 19 20 1
20 20 21 2
21 21 22 1
22 22 23 2
23 23 24 1
24 24 25 2
25 20 25 1
26 2 19 1 #Up
27 26 27 1
28 26 28 1
29 13 26 1 #Up
|
|---|
