| Entry |
|
|---|
| Name |
Tinlarebant (USAN) |
|---|
| Formula |
C21H21F5N4O2
|
|---|
| Exact mass |
456.1585
|
|---|
| Mol weight |
456.41
|
|---|
| Structure |
|
|---|
| Efficacy |
Optic nerve disease treatment, Retinol binding protein 4 antagonist |
|---|
| Comment |
Treatment of macular degeneration (AMD); Stargardt disease
|
|---|
| Target |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Not elsewhere classified
Organismal systems
Sensory system
RBP4
D12351 Tinlarebant (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 32
1 N1y N 9.5900 -13.8600
2 C1x C 9.5900 -15.2600
3 C1x C 10.8024 -15.9600
4 C8y C 12.0149 -15.2600
5 C8y C 12.0149 -13.8600
6 C1x C 10.8024 -13.1600
7 C8y C 13.3464 -15.6926
8 N5x N 14.1693 -14.5600
9 N4x N 13.3464 -13.4274
10 C5a C 8.3776 -13.1600
11 C1a C 7.1821 -13.8504
12 O5a O 8.3775 -11.7602
13 C5a C 13.7775 -17.0194
14 N1y N 15.1569 -17.3126
15 O5a O 12.8511 -18.0485
16 C1x C 15.5862 -18.6328
17 C1x C 16.9557 -18.9235
18 C1y C 17.8922 -17.8829
19 C1x C 17.4629 -16.5627
20 C1x C 16.0935 -16.2719
21 C8y C 19.2810 -18.1783
22 C8y C 19.7169 -19.5198
23 C8y C 21.0864 -19.8109
24 C8y C 22.0231 -18.7704
25 C8x C 21.5871 -17.4289
26 C8x C 20.2177 -17.1378
27 X F 23.4160 -19.0667
28 X F 21.5171 -21.1367
29 C1d C 18.7857 -20.5544
30 X F 17.7958 -19.5644
31 X F 19.7757 -21.5443
32 X F 17.7958 -21.5443
BOND 35
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 2
9 8 9 1
10 5 9 1
11 1 10 1
12 10 11 1
13 10 12 2
14 7 13 1
15 13 14 1
16 13 15 2
17 14 16 1
18 16 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 14 20 1
23 18 21 1
24 21 22 2
25 22 23 1
26 23 24 2
27 24 25 1
28 25 26 2
29 21 26 1
30 24 27 1
31 23 28 1
32 22 29 1
33 29 30 1
34 29 31 1
35 29 32 1
|
|---|
