KEGG   DRUG: Palopegteriparatide
Entry
D12395                      Drug                                   
Name
Palopegteriparatide (JAN/USAN/INN);
Yorvipath (TN)
Product
Sequence
XSVSEIQLMH NLGKHLNSME RVEWLRKKLQ DVHNF
  Type
Peptide
Class
Hormonal agent
 DG01661  Parathyroid hormone and parathyroid hormone-related protein analog
Remark
ATC code: H05AA05
Product: D12395<US>
Efficacy
Parathyroid hormone receptor agonist
  Disease
Hypoparathyroidism [DS:H01862]
Comment
Treatment of hypoparathyroidism
Target
PTH1R [HSA:5745] [KO:K04585]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04928  Parathyroid hormone synthesis, secretion and action
hsa04961  Endocrine and other factor-regulated calcium reabsorption
  Network
nt06318  CaSR-PTH signaling
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H05 CALCIUM HOMEOSTASIS
   H05A PARATHYROID HORMONES AND ANALOGUES
    H05AA Parathyroid hormones and analogues
     H05AA05 Palopegteriparatide
      D12395  Palopegteriparatide (JAN/USAN/INN) <US>
USP drug classification [BR:br08302]
 Metabolic Bone Disease Agents
  Calcium Regulating Hormones
   Palopegteriparatide
    D12395  Palopegteriparatide (JAN/USAN/INN)
Drug groups [BR:br08330]
 Hormonal agent
  DG01661  Parathyroid hormone and parathyroid hormone-related protein analog
   D12395  Palopegteriparatide
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Parathyroid hormone
    PTH1R
     D12395  Palopegteriparatide (JAN/USAN/INN) <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D12395
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D12395
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D12395
Other DBs
CAS: 2222514-07-8
PubChem: 497620808
LinkDB

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