KEGG   DRUG: Retatrutide
Entry
D12430                      Drug                                   
Name
Retatrutide (USAN)
Formula
C221H342N46O68
Exact mass
4728.4718
Mol weight
4731.34
Structure
Sequence
YXQGTFTSDY SILLDKKAQX AFIEYLLEGG PSSGAPPPS
  Type
Peptide
Efficacy
Antidiabetic, Antiobesity
  Type
Modified peptide
Comment
Glycemic control and obesity
Target
GCGR [HSA:2642] [KO:K04583]
GIPR [HSA:2696] [KO:K04580]
GLP1R [HSA:2740] [KO:K04581]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04911  Insulin secretion
hsa04922  Glucagon signaling pathway
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Glucagon
    GLP1R
     D12430  Retatrutide (USAN)
    GCGR
     D12430  Retatrutide (USAN)
   Gastric inhibitory polypeptide
    GIPR
     D12430  Retatrutide (USAN)
Other DBs
CAS: 2381089-83-2
PubChem: 497620843
LinkDB

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