| Entry |
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| Name |
Carfloglitazar (INN) |
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| Formula |
C36H29FN2O4
|
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| Exact mass |
572.2111
|
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| Mol weight |
572.62
|
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| Structure |
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| Class |
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
DG01732 Non-thiazolidinedione type PPAR agonist
|
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| Remark |
|
|---|
| Efficacy |
Antidiabetic, Peroxisome proliferator-activated receptor (PPAR) agonist |
|---|
| Target |
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| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A10 DRUGS USED IN DIABETES
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
A10BX Other blood glucose lowering drugs, excl. insulins
A10BX17 Carfloglitazar
D12484 Carfloglitazar (INN)
Drug groups [BR:br08330]
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
DG01732 Non-thiazolidinedione type PPAR agonist
D12484 Carfloglitazar
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
NR1C1 (PPARA)
D12484 Carfloglitazar (INN)
NR1C3 (PPARG)
D12484 Carfloglitazar (INN)
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 43
1 C8y C 23.1700 -17.7800
2 C8x C 23.1700 -19.1800
3 C8x C 21.9100 -19.8800
4 C8y C 20.7200 -19.1800
5 C8x C 20.7200 -17.7800
6 C8x C 21.9100 -17.0800
7 O2a O 19.5300 -19.8800
8 C1b C 18.3400 -19.1800
9 C1b C 17.1500 -19.8800
10 N4y N 15.9600 -19.1800
11 C8y C 14.7000 -19.7400
12 C8y C 13.7900 -18.6900
13 C8y C 14.4200 -17.5700
14 C8y C 15.8200 -17.8500
15 C8x C 14.0000 -16.1700
16 C8x C 14.9800 -15.1900
17 C8x C 16.3100 -15.4700
18 C8x C 16.7300 -16.8000
19 C8x C 14.2800 -21.0700
20 C8x C 12.8800 -21.3500
21 C8x C 11.9700 -20.3700
22 C8x C 12.3900 -19.0400
23 C1b C 24.3766 -17.0700
24 C1c C 25.5863 -17.7553
25 C6a C 26.8066 -17.0370
26 N1b N 25.5976 -19.1798
27 C8y C 26.8324 -19.8800
28 C8y C 26.8434 -21.2796
29 C8x C 28.0612 -21.9701
30 C8x C 29.2682 -21.2607
31 C8x C 29.2572 -19.8611
32 C8x C 28.0394 -19.1706
33 C5a C 25.6117 -22.0039
34 O5a O 24.3898 -21.3116
35 C8y C 25.6229 -23.3800
36 C8x C 24.4141 -24.0912
37 C8x C 24.4255 -25.4911
38 C8y C 25.6436 -26.1812
39 C8x C 26.7825 -25.4700
40 C8x C 26.8411 -24.0701
41 O6a O 28.0158 -17.7213
42 O6a O 26.7943 -15.6101
43 X F 25.6035 -27.5790
BOND 48
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 10 14 1
16 13 15 2
17 15 16 1
18 16 17 2
19 17 18 1
20 14 18 2
21 11 19 2
22 19 20 1
23 20 21 2
24 21 22 1
25 12 22 2
26 1 23 1
27 23 24 1
28 24 25 1
29 24 26 1
30 26 27 1
31 27 28 2
32 28 29 1
33 29 30 2
34 30 31 1
35 31 32 2
36 27 32 1
37 28 33 1
38 33 34 2
39 33 35 1
40 35 36 2
41 36 37 1
42 37 38 2
43 38 39 1
44 39 40 2
45 35 40 1
46 25 41 1
47 25 42 2
48 38 43 1
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