| Entry |
|
|---|
| Name |
Fipravirimat (USAN/INN) |
|---|
| Formula |
C43H67FN2O4S
|
|---|
| Exact mass |
726.4806
|
|---|
| Mol weight |
727.07
|
|---|
| Structure |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiviral, Maturation inhibitor |
|---|
| Comment |
Treatment of human immunodeficiency virus (HIV) infection
|
|---|
| Target |
|
|---|
| Pathway |
| ko03260 | Virion - Human immunodeficiency virus |
|
|---|
| Brite |
Antimicrobials [BR:br08307]
Antivirals
Virus maturation inhibitor
HIV maturation inhibitor
D12523 Fipravirimat (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 51
1 C1x C 7.6300 -13.4400
2 C1z C 7.6300 -14.8400
3 C1x C 8.8200 -15.5400
4 C1x C 10.0800 -14.8400
5 C2y C 10.0800 -13.4400
6 C2x C 8.8200 -12.7400
7 C6a C 6.4400 -15.5400
8 C2y C 11.2700 -12.7400
9 O6a O 5.2500 -14.8400
10 O6a O 6.4400 -16.9400
11 C1b C 6.4400 -14.1400
12 X F 6.4400 -12.7400
13 C1z C 12.4600 -13.4400
14 C1y C 13.7200 -12.7400
15 C1z C 13.7200 -11.3400
16 C1x C 12.5300 -10.6400
17 C2x C 11.2700 -11.3400
18 C1x C 14.9100 -13.4400
19 C1x C 16.1000 -12.7400
20 C1z C 16.1000 -11.3400
21 C1y C 14.9100 -10.6400
22 C1z C 17.3600 -10.6400
23 C1y C 17.3600 -9.2400
24 C1x C 16.1000 -8.5400
25 C1x C 14.9100 -9.2400
26 C1x C 18.5500 -11.3400
27 C1x C 19.7400 -10.6400
28 C1z C 19.7400 -9.2400
29 C1y C 18.5500 -8.5400
30 C1x C 20.7900 -8.2600
31 C1x C 20.2300 -7.0000
32 C1y C 18.8300 -7.1400
33 C2c C 17.9200 -6.0900
34 C2a C 16.5200 -6.3700
35 C1a C 18.3400 -4.7600
36 N1b N 20.9300 -9.9400
37 C1b C 22.1200 -9.2400
38 C1b C 23.3100 -9.9400
39 N1y N 24.5000 -9.2400
40 C1x C 24.5000 -7.8400
41 C1x C 25.6900 -9.9400
42 C1x C 26.9500 -9.2400
43 S2x S 26.9500 -7.8400
44 C1x C 25.6900 -7.1400
45 O3c O 26.9500 -6.4400
46 O3c O 28.1624 -8.5400
47 C1a C 17.3600 -12.0400
48 C1a C 16.1000 -9.9400
49 C1a C 13.7200 -9.9400
50 C1a C 11.2476 -14.1400
51 C1a C 12.4600 -14.8400
BOND 57
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 2
6 1 6 1
7 2 7 1 #Down
8 5 8 1
9 7 9 2
10 7 10 1
11 2 11 1 #Up
12 11 12 1
13 8 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 8 17 2
19 14 18 1
20 18 19 1
21 19 20 1
22 20 21 1
23 15 21 1
24 20 22 1
25 22 23 1
26 23 24 1
27 24 25 1
28 21 25 1
29 22 26 1
30 26 27 1
31 27 28 1
32 23 29 1
33 28 29 1
34 28 30 1
35 30 31 1
36 31 32 1
37 29 32 1
38 32 33 1 #Down
39 33 34 2
40 33 35 1
41 28 36 1 #Up
42 36 37 1
43 37 38 1
44 38 39 1
45 40 39 1
46 39 41 1
47 41 42 1
48 42 43 1
49 43 44 1
50 40 44 1
51 43 45 2
52 43 46 2
53 22 47 1 #Down
54 20 48 1 #Up
55 15 49 1 #Up
56 13 50 1 #Down
57 13 51 1 #Up
|
|---|
