KEGG   DRUG: Exagamglogene autotemcel
Entry
D12749                      Drug                                   
Name
Exagamglogene autotemcel (USAN/INN);
Casgevy (TN)
Product
CASGEVY (Vertex Pharmaceuticals Incorporated)
Remark
ATC code: B06AX05
Product: D12749<US>
Efficacy
Hematologic disease treatment
  Disease
Sickle cell disease [DS:H00229]
  Type
Cellular therapy product
Comment
Treatment of hemoglobinopathies such as severe sickle cell disease and transfusion dependent beta-thalassemia
Target
CD34 [HSA:947] [KO:K06474]
  Pathway
hsa04514  Cell adhesion molecules
hsa04640  Hematopoietic cell lineage
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B06 OTHER HEMATOLOGICAL AGENTS
   B06A OTHER HEMATOLOGICAL AGENTS
    B06AX Other hematological agents
     B06AX05 Exagamglogene autotemcel
      D12749  Exagamglogene autotemcel (USAN/INN) <US>
Target-based classification of drugs [BR:br08310]
 Cell surface molecules and ligands
  Other cell surface molecules
   CD molecules
    CD34
     D12749  Exagamglogene autotemcel (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
 Cellular and gene therapy products
  D12749
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D12749
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D12749
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