KEGG   DRUG: Povetacicept
Entry
D12803                      Drug                                   
Name
Povetacicept (USAN/INN)
Formula
C2756H4250N754O860S28
Exact mass
62564.4188
Mol weight
62603.65
Sequence
SLSCRKEQGE YYDHLLRDCI SCASICGQHP KQCADFCENK LRSGSGGGGS EPKSSDKTHT
CPPCPAPEAE GAPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH
NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE
PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF
LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP G
(Disulfide bridge: 4-19, 22-33, 26-37, 61-61', 64-64', 96-156, 202-260, 4'-19', 22'-33', 26'-37', 96'-156', 202'-260')
  Type
Peptide
Efficacy
Anti-inflammatory
Comment
Treatment of inflammatory conditions where b cell activating factor (BAFF) and/or a proliferation inducting ligand (APRIL) may be implicated
Target
TNFRSF13B (CD267, TACI) [HSA:23495] [KO:K05150]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04672  Intestinal immune network for IgA production
Brite
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   Tumor necrosis factor receptors
    TNFRSF13B (CD267, TACI)
     D12803  Povetacicept (USAN/INN)
Other DBs
CAS: 2490217-42-8
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