| Entry |
|
|---|
| Name |
Mevrometostat (USAN) |
|---|
| Formula |
C22H24Cl2N2O5
|
|---|
| Exact mass |
466.1062
|
|---|
| Mol weight |
467.34
|
|---|
| Structure |
|
|---|
| Efficacy |
Antineoplastic, Histone methyltransferase inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Enzymes
Transferases (EC2)
Methyltransferases
EZH2
D12845 Mevrometostat (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 31
1 C8y C 8.1900 -15.8200
2 C8x C 8.1900 -17.2200
3 C8y C 9.4024 -17.9200
4 C8y C 10.6149 -17.2200
5 C8y C 10.6149 -15.8200
6 C8y C 9.4024 -15.1200
7 C1x C 11.8273 -17.9200
8 C1x C 13.0397 -17.2200
9 N1y N 13.0397 -15.8200
10 C5x C 11.8273 -15.1200
11 C1b C 14.2373 -15.1285
12 C8y C 15.4256 -15.8145
13 C8y C 15.4257 -17.2198
14 N4x N 16.6381 -17.9197
15 C8y C 17.8505 -17.2196
16 C8x C 17.8504 -15.8144
17 C8y C 16.6380 -15.1145
18 C1c C 6.9776 -15.1200
19 C1y C 5.7821 -15.8104
20 C1x C 4.4582 -15.4559
21 O2x O 4.1037 -16.7798
22 C1x C 5.4275 -17.1343
23 O2a O 6.9775 -13.7202
24 C1a C 5.7819 -13.0298
25 X Cl 9.4024 -13.7202
26 X Cl 9.4024 -19.3198
27 O5x O 11.8273 -13.7200
28 O2a O 16.6380 -13.7202
29 C1a C 15.4421 -13.0296
30 C1a C 19.0628 -17.9194
31 O5x O 14.1941 -17.9312
BOND 34
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 15 16 2
18 16 17 1
19 12 17 2
20 1 18 1
21 18 19 1
22 19 20 1
23 20 21 1
24 21 22 1
25 19 22 1
26 18 23 1 #Up
27 23 24 1
28 6 25 1
29 3 26 1
30 10 27 2
31 17 28 1
32 28 29 1
33 15 30 1
34 13 31 2
|
|---|
