KEGG   DRUG: Pemvidutide
Entry
D12861                      Drug                                   
Name
Pemvidutide (USAN/INN)
Formula
C182H275N39O54
Exact mass
3870.9972
Mol weight
3873.36
Structure
Sequence
HXQGTFTSDY SKYLDEKAAK EFIQWLLQT
  Type
Peptide
Class
Antidiabetic agent
 DG02044  Hypoglycemic agent
  DG01493  GLP-1 receptor agonist
Unclassified
 DG03355  Oxyntomodulin analog
Efficacy
Antiobesity, Glucagon-like peptide 1 (GLP-1) receptor agonist, Glucagon receptor agonist
  Type
Modified peptide
Comment
Treatment of non-alcoholic steatohepatitis (NASH) and obesity
Target
GLP1R [HSA:2740] [KO:K04581]
GCGR [HSA:2642] [KO:K04583]
  Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04911  Insulin secretion
hsa04922  Glucagon signaling pathway
Interaction
Brite
Drug groups [BR:br08330]
 Antidiabetic agent
  DG02044  Hypoglycemic agent
   DG01493  GLP-1 receptor agonist
    D12861  Pemvidutide
 Unclassified
  DG03355  Oxyntomodulin analog
   D12861  Pemvidutide
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Glucagon
    GLP1R
     D12861  Pemvidutide (USAN/INN)
    GCGR
     D12861  Pemvidutide (USAN/INN)
Other DBs
CAS: 2538014-94-5
PubChem: 497621274
LinkDB

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