| Entry |
|
|---|
| Name |
Pimicotinib (USAN/INN) |
|---|
| Formula |
C22H24N6O3
|
|---|
| Exact mass |
420.1910
|
|---|
| Mol weight |
420.46
|
|---|
| Structure |
|
|---|
| Remark |
|
|---|
| Efficacy |
Anti-inflammatory, Antineoplastic, Macrophage colony-stimulating factor receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04060 | Cytokine-cytokine receptor interaction |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Cytokines and receptors
Cytokine receptors
CSF and other factor receptors
CSF1R (FMS, CD115)
D12938 Pimicotinib (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 31
1 O2a O 22.1900 -17.3600
2 C8y C 21.0000 -16.6600
3 C8x C 21.0000 -15.2600
4 C8x C 19.7400 -14.5600
5 C8y C 18.5500 -15.2600
6 N5x N 18.5500 -16.6600
7 C8y C 19.7400 -17.3600
8 N1b N 17.3600 -14.5600
9 C5a C 17.3600 -13.1600
10 O5a O 18.5500 -12.4600
11 N1y N 16.1700 -12.4600
12 C1x C 15.7500 -11.1300
13 C1x C 14.3500 -11.1300
14 C1z C 13.8600 -12.4600
15 C5x C 14.9800 -13.3000
16 C1a C 19.7400 -18.7600
17 O5x O 14.9800 -14.7000
18 C1a C 12.5300 -12.8800
19 C1a C 12.8800 -11.4100
20 C8y C 23.4500 -16.6600
21 C8x C 23.4500 -15.2600
22 C8x C 24.6400 -17.3600
23 C8y C 25.9000 -16.6600
24 N5x N 25.9000 -15.2600
25 C8x C 24.6400 -14.5600
26 C8y C 27.1066 -17.3700
27 C8x C 27.5587 -18.6792
28 N5x N 28.9469 -18.6569
29 N4y N 29.3547 -17.3298
30 C8x C 28.2185 -16.5319
31 C1a C 30.6477 -16.8871
BOND 34
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 2
5 5 6 1
6 6 7 2
7 2 7 1
8 5 8 1
9 8 9 1
10 9 10 2
11 9 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 11 15 1
17 7 16 1
18 15 17 2
19 14 18 1
20 14 19 1
21 1 20 1
22 21 20 2
23 20 22 1
24 22 23 2
25 23 24 1
26 24 25 2
27 21 25 1
28 23 26 1
29 26 27 1
30 27 28 2
31 28 29 1
32 29 30 1
33 26 30 2
34 29 31 1
|
|---|
