| Entry |
|
|---|
| Name |
Inaxaplin (USAN/INN) |
|---|
| Formula |
C21H18F3N3O3
|
|---|
| Exact mass |
417.1300
|
|---|
| Mol weight |
417.38
|
|---|
| Structure |
|
|---|
| Efficacy |
Apolipoprotein L1 inhibitor |
|---|
| Comment |
Treatment of APOL1-mediated kidney disease in individuals with 2 apolipoprotein L1 mutations
|
|---|
| Target |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Not elsewhere classified
Organismal systems
Digestive system
APOL1
D12964 Inaxaplin (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 30
1 C8y C 11.8300 -15.8900
2 C1b C 13.0200 -16.5900
3 C1b C 14.2100 -15.8900
4 C5a C 15.4000 -16.5900
5 N1b N 16.5900 -15.8900
6 O5a O 15.4000 -17.9900
7 C1y C 17.7800 -16.5900
8 C5x C 17.7800 -17.9900
9 N1x N 19.0400 -18.4800
10 C1x C 19.9500 -17.3600
11 C1y C 19.1800 -16.2400
12 O5x O 16.5900 -18.7600
13 O1a O 19.6700 -14.9100
14 C8y C 11.8300 -14.4900
15 N4x N 10.5000 -14.0700
16 C8y C 9.6600 -15.1900
17 C8y C 10.5000 -16.3100
18 C8y C 12.9500 -13.7200
19 C8x C 12.9500 -12.3200
20 C8x C 14.1400 -14.4200
21 C8x C 15.4000 -13.7200
22 C8y C 15.4000 -12.3200
23 C8x C 14.1400 -11.6200
24 X F 16.6066 -11.6100
25 C8y C 8.2701 -15.3575
26 C8x C 7.7201 -16.6449
27 C8y C 8.5601 -17.7649
28 C8x C 9.9501 -17.5975
29 X F 8.0018 -19.0724
30 X F 7.4131 -14.2152
BOND 33
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 4 6 2
6 7 5 1 #Up
7 7 8 1
8 8 9 1
9 9 10 1
10 10 11 1
11 7 11 1
12 8 12 2
13 11 13 1 #Down
14 1 14 2
15 14 15 1
16 15 16 1
17 1 17 1
18 14 18 1
19 19 18 2
20 18 20 1
21 20 21 2
22 21 22 1
23 22 23 2
24 19 23 1
25 22 24 1
26 17 16 2
27 16 25 1
28 25 26 2
29 26 27 1
30 27 28 2
31 17 28 1
32 27 29 1
33 25 30 1
|
|---|
